Detalhe da pesquisa
1.
SnapShot: N-Glycosylation Processing Pathways across Kingdoms.
Cell
; 171(1): 258-258.e1, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938118
2.
Elucidating uptake and metabolic fate of dipeptides in CHO cell cultures using 13C labeling experiments and kinetic modeling.
Metab Eng
; 83: 12-23, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460784
3.
Reconstruction of reverse transsulfuration pathway enables cysteine biosynthesis and enhances resilience to oxidative stress in Chinese Hamster Ovary cells.
Metab Eng
; 76: 204-214, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36822463
4.
Overexpression of peroxisome proliferator-activated receptor γ co-activator-1⺠(PGC-1âº) in Chinese hamster ovary cells increases oxidative metabolism and IgG productivity.
Metab Eng
; 79: 108-117, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37473833
5.
Metabolic engineering of Synechococcus elongatus 7942 for enhanced sucrose biosynthesis.
Metab Eng
; 80: 12-24, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37678664
6.
CHOGlycoNET: Comprehensive glycosylation reaction network for CHO cells.
Metab Eng
; 76: 87-96, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36610518
7.
Addressing amino acid-derived inhibitory metabolites and enhancing CHO cell culture performance through DOE-guided media modifications.
Biotechnol Bioeng
; 120(9): 2542-2558, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37096798
8.
Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing.
Biotechnol Bioeng
; 120(11): 3148-3162, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37475681
9.
Chemical inhibitors of hexokinase-2 enzyme reduce lactate accumulation, alter glycosylation processing, and produce altered glycoforms in CHO cell cultures.
Biotechnol Bioeng
; 120(9): 2559-2577, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148536
10.
Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing.
Biotechnol Bioeng
; 120(3): 715-725, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36411514
11.
Comprehensive N- and O-Glycoproteomic Analysis of Multiple Chinese Hamster Ovary Host Cell Lines.
J Proteome Res
; 21(10): 2341-2355, 2022 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36129246
12.
Association of Frailty, Age, and Biological Sex With Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine-Induced Immunity in Older Adults.
Clin Infect Dis
; 75(Suppl 1): S61-S71, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35607747
13.
Significant impact of mTORC1 and ATF4 pathways in CHO cell recombinant protein production induced by CDK4/6 inhibitor.
Biotechnol Bioeng
; 119(5): 1189-1206, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35112712
14.
Engineering redox sensors into CHO cells enables near-real-time quantification of intracellular redox in bioprocesses.
Biotechnol Bioeng
; 119(6): 1439-1449, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182429
15.
A proteomics approach to decipher a sticky CHO situation.
Biotechnol Bioeng
; 119(8): 2064-2075, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35470426
16.
Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages.
Biotechnol Bioeng
; 119(4): 1062-1076, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35028935
17.
Attenuation of glutamine synthetase selection marker improves product titer and reduces glutamine overflow in Chinese hamster ovary cells.
Biotechnol Bioeng
; 119(7): 1712-1727, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35312045
18.
A genome-scale nutrient minimization forecast algorithm for controlling essential amino acid levels in CHO cell cultures.
Biotechnol Bioeng
; 119(2): 435-451, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34811743
19.
The interplay of protein engineering and glycoengineering to fine-tune antibody glycosylation and its impact on effector functions.
Biotechnol Bioeng
; 119(1): 102-117, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34647616
20.
Metabolic analysis of the asparagine and glutamine dynamics in an industrial Chinese hamster ovary fed-batch process.
Biotechnol Bioeng
; 119(3): 807-819, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34786689