Detalhe da pesquisa
1.
Distinct changes in endosomal composition promote NLRP3 inflammasome activation.
Nat Immunol
; 24(1): 30-41, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36443515
2.
Coatopathies: Genetic Disorders of Protein Coats.
Annu Rev Cell Dev Biol
; 35: 131-168, 2019 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31399000
3.
Lysosomes as dynamic regulators of cell and organismal homeostasis.
Nat Rev Mol Cell Biol
; 21(2): 101-118, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768005
4.
Structural Mechanism for Cargo Recognition by the Retromer Complex.
Cell
; 167(6): 1623-1635.e14, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889239
5.
Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aß Pool.
Cell
; 166(1): 193-208, 2016 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27293189
6.
Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER.
Cell
; 154(3): 609-22, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23890821
7.
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1.
Cell
; 152(4): 755-67, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23415225
8.
Lysosome Positioning Influences mTORC2 and AKT Signaling.
Mol Cell
; 75(1): 26-38.e3, 2019 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31130364
9.
A neurodevelopmental disorder associated with an activating de novo missense variant in ARF1.
Hum Mol Genet
; 32(7): 1162-1174, 2023 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36345169
10.
Biallelic BORCS8 variants cause an infantile-onset neurodegenerative disorder with altered lysosome dynamics.
Brain
; 147(5): 1751-1767, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38128568
11.
AP2A2 mutation and defective endocytosis in a Malian family with hereditary spastic paraplegia.
Neurobiol Dis
; 198: 106537, 2024 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-38772452
12.
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.
PLoS Biol
; 19(7): e3001287, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34283825
13.
A myosin-7B-dependent endocytosis pathway mediates cellular entry of α-synuclein fibrils and polycation-bearing cargos.
Proc Natl Acad Sci U S A
; 117(20): 10865-10875, 2020 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366666
14.
Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.
PLoS Genet
; 16(12): e1009259, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33362196
15.
The ubiquitin isopeptidase USP10 deubiquitinates LC3B to increase LC3B levels and autophagic activity.
J Biol Chem
; 296: 100405, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577797
16.
Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning.
PLoS Biol
; 17(5): e3000279, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31100061
17.
A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1.
BMC Biol
; 19(1): 218, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34592985
18.
A neurodevelopmental disorder caused by mutations in the VPS51 subunit of the GARP and EARP complexes.
Hum Mol Genet
; 28(9): 1548-1560, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30624672
19.
Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome.
PLoS Genet
; 14(4): e1007363, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698489
20.
The role of AP-4 in cargo export from the trans-Golgi network and hereditary spastic paraplegia.
Biochem Soc Trans
; 48(5): 1877-1888, 2020 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33084855