Detalhe da pesquisa
1.
Recent advances in upstream process development for production of recombinant adeno-associated virus.
Biotechnol Bioeng
; 121(1): 53-70, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37691172
2.
Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step.
Biotechnol Bioeng
; 118(9): 3334-3347, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33624836
3.
Online monitoring and control of upstream cell culture process using 1D and 2D-LC with SegFlow interface.
Biotechnol Bioeng
; 118(9): 3593-3603, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34185315
4.
A CFD model for predicting protein aggregation in low-pH virial inactivation for mAb production.
Biotechnol Bioeng
; 117(11): 3400-3412, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672835
5.
Technology outlook for real-time quality attribute and process parameter monitoring in biopharmaceutical development-A review.
Biotechnol Bioeng
; 117(10): 3182-3198, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946122
6.
Hypoxia and transforming growth factor-beta1 pathway activation promote Chinese Hamster Ovary cell aggregation.
Biotechnol Bioeng
; 115(4): 1051-1061, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29251349
7.
Early identification of unusually clustered mutations and root causes in therapeutic antibody development.
Biotechnol Bioeng
; 115(9): 2377-2382, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29777592
8.
Advances in analytical methodologies to guide bioprocess engineering for bio-therapeutics.
Methods
; 116: 63-83, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27832969
9.
A carbon dioxide stripping model for mammalian cell culture in manufacturing scale bioreactors.
Biotechnol Bioeng
; 114(6): 1184-1194, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27922179
10.
The use of 'Omics technology to rationally improve industrial mammalian cell line performance.
Biotechnol Bioeng
; 113(1): 26-38, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26059229
11.
Validation of a CFD model for cell culture bioreactors at large scale and its application in scale-up.
J Biotechnol
; 387: 79-88, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582408
12.
Use of spectroscopic process analytical technology for rapid quality evaluation during preparation of CHO cell culture media.
Biotechnol Prog
; : e3477, 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38699906
13.
Strategies for controlling afucosylation in monoclonal antibodies during upstream manufacturing.
Biotechnol J
; 18(7): e2200604, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37029472
14.
Antibody charge variant modulation by in vitro enzymatic treatment in different Chinese hamster ovary cell cultures.
Biotechnol Prog
; 38(5): e3268, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35536540
15.
Upstream cell culture process characterization and in-process control strategy development at pandemic speed.
MAbs
; 14(1): 2060724, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35380922
16.
N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing.
Bioengineering (Basel)
; 9(4)2022 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447688
17.
Improved Titer in Late-Stage Mammalian Cell Culture Manufacturing by Re-Cloning.
Bioengineering (Basel)
; 9(4)2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447733
18.
Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in-line Raman spectroscopy probe.
Biotechnol Bioeng
; 108(5): 1215-21, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21449033
19.
High throughput screening data for a case study of CHO cell culture process development.
Data Brief
; 39: 107491, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34712760
20.
Effects of culture conditions on N-glycolylneuraminic acid (Neu5Gc) content of a recombinant fusion protein produced in CHO cells.
Biotechnol Bioeng
; 105(6): 1048-57, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20039310