Detalhe da pesquisa
1.
Factors of significance for the ability of fighter pilots to visually indicate the magnitude of roll tilt during simulated turns in a centrifuge.
Perception
; 53(2): 75-92, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37946509
2.
Addressing Today's Absorption, Distribution, Metabolism, and Excretion (ADME) Challenges in the Translation of In Vitro ADME Characteristics to Humans: A Case Study of the SMN2 mRNA Splicing Modifier Risdiplam.
Drug Metab Dispos
; 50(1): 65-75, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34620695
3.
In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK).
Invest New Drugs
; 40(1): 68-80, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417912
4.
Characterization of the pharmacokinetics of entrectinib and its active M5 metabolite in healthy volunteers and patients with solid tumors.
Invest New Drugs
; 39(3): 803-811, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462752
5.
Safety, Tissue Distribution, and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats.
Toxicol Pathol
; 49(6): 1174-1192, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060347
6.
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
J Am Soc Nephrol
; 31(12): 2773-2792, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938648
7.
Detecting cocoa plantations in Côte d'Ivoire and Ghana and their implications on protected areas.
Ecol Indic
; 129: 107863, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34602863
8.
Genotoxicity Assessment of Drug Metabolites in the Context of MIST and Beyond.
Chem Res Toxicol
; 33(1): 10-19, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31859487
9.
Qualification of impurities based on metabolite data.
Regul Toxicol Pharmacol
; 110: 104524, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734179
10.
Structure-metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds.
Proc Natl Acad Sci U S A
; 114(16): E3178-E3187, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373537
11.
Drug-induced Obstructive and Retrograde Nephropathy Associated with α2u-globulin in Male Rats.
Toxicol Pathol
; 47(2): 138-149, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587097
12.
Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry.
Anal Chem
; 89(12): 6821-6826, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28520401
13.
Software-aided cytochrome P450 reaction phenotyping and kinetic analysis in early drug discovery.
Rapid Commun Mass Spectrom
; 30(2): 301-10, 2016 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26689160
14.
Determination of tropical deforestation rates and related carbon losses from 1990 to 2010.
Glob Chang Biol
; 20(8): 2540-54, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24753029
15.
Post-acquisition analysis of untargeted accurate mass quadrupole time-of-flight MS(E) data for multiple collision-induced neutral losses and fragment ions of glutathione conjugates.
Rapid Commun Mass Spectrom
; 28(24): 2695-703, 2014 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25380491
16.
Software aided approaches to structure-based metabolite identification in drug discovery and development.
Drug Discov Today Technol
; 10(1): e207-17, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24050249
17.
Visual measures of perceived roll tilt in pilots during coordinated flight and gondola centrifugation.
J Vestib Res
; 33(1): 1-19, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36442173
18.
Detection and Characterization of Walking Bouts Using a Single Wrist-Worn Accelerometer in Free-living Conditions.
medRxiv
; 2023 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577642
19.
Investigating discovery strategies and pharmacological properties of stereodefined phosphorodithioate LNA gapmers.
Mol Ther Nucleic Acids
; 29: 176-188, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35860384
20.
A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study.
JMIR Aging
; 5(2): e35696, 2022 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35536617