Detalhe da pesquisa
1.
Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human MYBPC3 HCM.
Circ Res
; 132(5): 628-644, 2023 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36744470
2.
Lysosomal calcium loading promotes spontaneous calcium release by potentiating ryanodine receptors.
Biophys J
; 122(15): 3044-3059, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37329137
3.
What determines the optimal pharmacological treatment of atrial fibrillation? Insights from in silico trials in 800 virtual atria.
J Physiol
; 601(18): 4013-4032, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37475475
4.
CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Circ Res
; 129(2): 326-341, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34018815
5.
Homogenisation for the monodomain model in the presence of microscopic fibrotic structures.
Commun Nonlinear Sci Numer Simul
; 116: None, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37113591
6.
Remodelling of potassium currents underlies arrhythmic action potential prolongation under beta-adrenergic stimulation in hypertrophic cardiomyopathy.
J Mol Cell Cardiol
; 172: 120-131, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36058298
7.
The 'Digital Twin' to enable the vision of precision cardiology.
Eur Heart J
; 41(48): 4556-4564, 2020 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32128588
8.
From ionic to cellular variability in human atrial myocytes: an integrative computational and experimental study.
Am J Physiol Heart Circ Physiol
; 314(5): H895-H916, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29351467
9.
In Vivo and In Silico Investigation Into Mechanisms of Frequency Dependence of Repolarization Alternans in Human Ventricular Cardiomyocytes.
Circ Res
; 118(2): 266-78, 2016 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26602864
10.
Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities.
Europace
; 20(suppl_3): iii102-iii112, 2018 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30476051
11.
Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy.
J Mol Cell Cardiol
; 96: 72-81, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385634
12.
Human ventricular activation sequence and the simulation of the electrocardiographic QRS complex and its variability in healthy and intraventricular block conditions.
Europace
; 18(suppl 4): iv4-iv15, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28011826
13.
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.
Europace
; 18(9): 1287-98, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26622055
14.
Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology.
Proc Natl Acad Sci U S A
; 110(23): E2098-105, 2013 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23690584
15.
Na/K pump regulation of cardiac repolarization: insights from a systems biology approach.
Pflugers Arch
; 466(2): 183-93, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23674099
16.
Electrophysiological mechanisms underlying T wave pseudonormalisation on stress ECGs in hypertrophic cardiomyopathy.
Comput Biol Med
; 169: 107829, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096763
17.
Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy.
Front Pharmacol
; 15: 1379236, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659580
18.
Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study.
Cardiovasc Res
; 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38646743
19.
Comprehensive characterization of cardiac contraction for improved post-infarction risk assessment.
Sci Rep
; 14(1): 8951, 2024 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637609
20.
Digital twinning of the human ventricular activation sequence to Clinical 12-lead ECGs and magnetic resonance imaging using realistic Purkinje networks for in silico clinical trials.
Med Image Anal
; 94: 103108, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447244