Detalhe da pesquisa
1.
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Nature
; 622(7984): 850-862, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794185
2.
Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
PLoS Genet
; 10(9): e1004566, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25188243
3.
Sprouty proteins are negative regulators of interferon (IFN) signaling and IFN-inducible biological responses.
J Biol Chem
; 287(50): 42352-60, 2012 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23074222
4.
LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.
Cancer Discov
; 11(6): 1398-1410, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579786
5.
The extracellular matrix microtopography drives critical changes in cellular motility and Rho A activity in colon cancer cells.
Cancer Cell Int
; 10: 24, 2010 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20667086
6.
An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia.
Oncogene
; 38(5): 671-686, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30171259
7.
Activation of JAK/STAT Signaling in Megakaryocytes Sustains Myeloproliferation In Vivo.
Clin Cancer Res
; 25(19): 5901-5912, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217200
8.
A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis.
Cancer Cell
; 34(5): 707-723.e7, 2018 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423293
9.
ROCK-II mediates colon cancer invasion via regulation of MMP-2 and MMP-13 at the site of invadopodia as revealed by multiphoton imaging.
Lab Invest
; 87(11): 1149-58, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17876296
10.
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
Cell Rep
; 21(3): 628-640, 2017 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045832
11.
Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis.
PLoS One
; 11(9): e0162515, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27610619
12.
AKT activation is a feature of CALR mutant myeloproliferative neoplasms.
Leukemia
; 33(1): 271-274, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082822