Detalhe da pesquisa
1.
Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasion.
Nat Immunol
; 25(3): 483-495, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177283
2.
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functions.
Immunity
; 57(4): 876-889.e11, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38479384
3.
TMEM175 Is an Organelle K(+) Channel Regulating Lysosomal Function.
Cell
; 162(5): 1101-12, 2015 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26317472
4.
mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.
Cell
; 152(4): 778-790, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23394946
5.
Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.
PLoS Biol
; 22(4): e3002591, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38652732
6.
A growth-factor-activated lysosomal K+ channel regulates Parkinson's pathology.
Nature
; 591(7850): 431-437, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33505021
7.
Lysosomal Ion Channels: What Are They Good For and Are They Druggable Targets?
Annu Rev Pharmacol Toxicol
; 63: 19-41, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151054
8.
Metabolomic profiling of single enlarged lysosomes.
Nat Methods
; 18(7): 788-798, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34127857
9.
Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease.
EMBO Rep
; 23(9): e53234, 2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35913019
10.
In vivo labeling and quantitative imaging of neuronal populations using MRI.
Neuroimage
; 281: 120374, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729795
11.
The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature
; 547(7664): 472-475, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28723891
12.
Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana.
Nature
; 531(7593): 196-201, 2016 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26689363
13.
Author Correction: A growth-factor-activated lysosomal K+ channel regulates Parkinson's pathology.
Nature
; 592(7855): E10, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33790472
14.
Biallelic Mutations in UNC80 Cause Persistent Hypotonia, Encephalopathy, Growth Retardation, and Severe Intellectual Disability.
Am J Hum Genet
; 98(1): 202-9, 2016 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26708751
15.
The voltage-gated sodium channel TPC1 confers endolysosomal excitability.
Nat Chem Biol
; 10(6): 463-9, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24776928
16.
Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis.
Cell Death Discov
; 10(1): 256, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38802335
17.
Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington's disease.
Cell Rep
; 42(12): 113573, 2023 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38096054
18.
Structure of the Arabidopsis guard cell anion channel SLAC1 suggests activation mechanism by phosphorylation.
Nat Commun
; 13(1): 2511, 2022 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35523967
19.
Wnt8a is one of the candidate genes that play essential roles in the elongation of the seahorse prehensile tail.
Mar Life Sci Technol
; 3(4): 416-426, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37073259
20.
CLN7 is an organellar chloride channel regulating lysosomal function.
Sci Adv
; 7(51): eabj9608, 2021 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910516