Detalhe da pesquisa
1.
SerpinA1 levels in amyotrophic lateral sclerosis patients: An exploratory study.
Eur J Neurol
; 31(1): e16054, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679868
2.
A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism.
Mol Cell
; 63(5): 796-810, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27570075
3.
Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process.
J Am Chem Soc
; 145(28): 15188-15196, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37411010
4.
Defective ribosomal products challenge nuclear function by impairing nuclear condensate dynamics and immobilizing ubiquitin.
EMBO J
; 38(15): e101341, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31271238
5.
Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling.
EMBO Rep
; 22(5): e51740, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33738926
6.
ALS and FTD: Where RNA metabolism meets protein quality control.
Semin Cell Dev Biol
; 99: 183-192, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31254610
7.
Pathogenic variants of Valosin-containing protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells.
Neuropathol Appl Neurobiol
; 48(5): e12818, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501124
8.
Missense mutation in ATXN2 gene (c.2860C > T) in an amyotrophic lateral sclerosis patient with aggressive disease phenotype.
Neurol Sci
; 43(10): 6087-6090, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35731316
9.
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function.
EMBO J
; 36(12): 1669-1687, 2017 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28377462
10.
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Hum Mol Genet
; 25(18): 3908-3924, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466192
11.
Tardigrade small heat shock proteins can limit desiccation-induced protein aggregation.
Commun Biol
; 6(1): 121, 2023 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36717706
12.
Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly.
Sci Adv
; 9(13): eabq7585, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000881
13.
Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia.
Cell Death Discov
; 9(1): 248, 2023 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37454169
14.
Alternatively spliced exon regulates context-dependent MEF2D higher-order assembly during myogenesis.
Nat Commun
; 14(1): 1329, 2023 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36898987
15.
Human HSP70-escort protein 1 (hHep1) interacts with negatively charged lipid bilayers and cell membranes.
Cell Stress Chaperones
; 28(6): 1001-1012, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38001371
16.
The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins.
Cell Stress Chaperones
; 28(6): 621-629, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37462824
17.
HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones.
Hum Mol Genet
; 19(23): 4677-93, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20843828
18.
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS).
Hum Mol Genet
; 19(17): 3440-56, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20570967
19.
Case report: p.Glu134del SOD1 mutation in two apparently unrelated ALS patients with mirrored phenotype.
Front Neurol
; 13: 1052341, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36686515
20.
RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1.
Cells
; 11(2)2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35053410