Detalhe da pesquisa
1.
Metformin: Restraining Nucleocytoplasmic Shuttling to Fight Cancer and Aging.
Cell
; 167(7): 1670-1671, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27984715
2.
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
PLoS Genet
; 16(11): e1009083, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33253201
3.
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity.
Proc Natl Acad Sci U S A
; 116(42): 20817-20819, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570569
4.
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.
PLoS Genet
; 13(3): e1006593, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28253260
5.
Untangling Longevity, Dauer, and Healthspan in Caenorhabditis elegans Insulin/IGF-1-Signalling.
Gerontology
; 64(1): 96-104, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934747
6.
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
J Neurosci
; 36(46): 11654-11670, 2016 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27852774
7.
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction.
Brain
; 138(Pt 7): 1801-16, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001724
8.
[Molecular gerontology: towards healthy aging]. / Gerontología molecular: hacia un envejecimiento saludable.
Gac Med Mex
; 149(6): 680-5, 2013.
Artigo
em Espanhol
| MEDLINE | ID: mdl-24276192
9.
An antisteatosis response regulated by oleic acid through lipid droplet-mediated ERAD enhancement.
Sci Adv
; 9(1): eadc8917, 2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36598980
10.
Reply: Glial mitochondropathy in infantile neuroaxonal dystrophy: pathophysiological and therapeutic implications.
Brain
; 139(Pt 12): e68, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27497489
11.
The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease.
Neural Regen Res
; 12(3): 380-384, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28469644
12.
Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation.
Rare Dis
; 4(1): e1128616, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27141409
13.
Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.
Cell Rep
; 15(3): 638-650, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068460
14.
Genetics and pharmacology of longevity: the road to therapeutics for healthy aging.
Adv Genet
; 90: 1-101, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26296933
15.
From white to brown fat through the PGC-1α-dependent myokine irisin: implications for diabetes and obesity.
Dis Model Mech
; 5(3): 293-5, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566556
16.
Parkin' control: regulation of PGC-1α through PARIS in Parkinson's disease.
Dis Model Mech
; 4(4): 427-9, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21708898