Detalhe da pesquisa
1.
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.
Cell
; 185(13): 2213-2233.e25, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750033
2.
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Am J Hum Genet
; 107(1): 96-110, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589923
3.
Genetic Modification of Huntington Disease Acts Early in the Prediagnosis Phase.
Am J Hum Genet
; 103(3): 349-357, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30122542
4.
Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples.
Psychol Med
; 51(7): 1147-1156, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31955720
5.
Population-specific genetic modification of Huntington's disease in Venezuela.
PLoS Genet
; 14(5): e1007274, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29750799
6.
Sex differences in the genetic predictors of Alzheimer's pathology.
Brain
; 142(9): 2581-2589, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31497858
7.
A modifier of Huntington's disease onset at the MLH1 locus.
Hum Mol Genet
; 26(19): 3859-3867, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934397
8.
Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9.
Hum Mol Genet
; 25(20): 4566-4576, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28172889
9.
Sequence-Level Analysis of the Major European Huntington Disease Haplotype.
Am J Hum Genet
; 97(3): 435-44, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320893
10.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Acta Neuropathol
; 136(6): 857-872, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29967939
11.
Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.
Hum Mol Genet
; 19(18): 3679-89, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20634196
12.
Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
PLoS Genet
; 5(2): e1000369, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19197344
13.
Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
Proc Natl Acad Sci U S A
; 106(18): 7542-7, 2009 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19380721
14.
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
Nat Neurosci
; 25(4): 446-457, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35379994
15.
Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.
Hum Mol Genet
; 18(2): 261-6, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19098025
16.
HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
Proc Natl Acad Sci U S A
; 105(35): 13069-74, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18765817
17.
Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases.
Nat Commun
; 12(1): 5071, 2021 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417470
18.
Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease.
J Huntingtons Dis
; 10(3): 367-375, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180418
19.
Dysregulation of mitochondrial and proteolysosomal genes in Parkinson's disease myeloid cells.
Nat Aging
; 1(9): 850-863, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35005630
20.
The inheritance of resistance alleles in multiple sclerosis.
PLoS Genet
; 3(9): 1607-13, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17845076