Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

One Ring to Rule Them All: Mitochondrial Circular RNAs Control Mitochondrial Function.

Yan, Lichong; Chen, Y Grace.

Cell ; 183(1): 11-13, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-33007261

2.

Cellular origins of dsRNA, their recognition and consequences.

Chen, Y Grace; Hur, Sun.

Nat Rev Mol Cell Biol ; 23(4): 286-301, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-34815573

3.

Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.

Cho, Seung Woo; Xu, Jin; Sun, Ruping; Mumbach, Maxwell R; Carter, Ava C; Chen, Y Grace; Yost, Kathryn E; Kim, Jeewon; He, Jing; Nevins, Stephanie A; Chin, Suet-Feung; Caldas, Carlos; Liu, S John; Horlbeck, Max A; Lim, Daniel A; Weissman, Jonathan S; Curtis, Christina; Chang, Howard Y.

Cell ; 173(6): 1398-1412.e22, 2018 05 31.

Artigo em Inglês | MEDLINE | ID: mdl-29731168

4.

Gene regulation in the immune system by long noncoding RNAs.

Chen, Y Grace; Satpathy, Ansuman T; Chang, Howard Y.

Nat Immunol ; 18(9): 962-972, 2017 Aug 22.

Artigo em Inglês | MEDLINE | ID: mdl-28829444

5.

Inflammasome activation in infected macrophages drives COVID-19 pathology.

Sefik, Esen; Qu, Rihao; Junqueira, Caroline; Kaffe, Eleanna; Mirza, Haris; Zhao, Jun; Brewer, J Richard; Han, Ailin; Steach, Holly R; Israelow, Benjamin; Blackburn, Holly N; Velazquez, Sofia E; Chen, Y Grace; Halene, Stephanie; Iwasaki, Akiko; Meffre, Eric; Nussenzweig, Michel; Lieberman, Judy; Wilen, Craig B; Kluger, Yuval; Flavell, Richard A.

Nature ; 606(7914): 585-593, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35483404

6.

N6-Methyladenosine Modification Controls Circular RNA Immunity.

Chen, Y Grace; Chen, Robert; Ahmad, Sadeem; Verma, Rohit; Kasturi, Sudhir Pai; Amaya, Laura; Broughton, James P; Kim, Jeewon; Cadena, Cristhian; Pulendran, Bali; Hur, Sun; Chang, Howard Y.

Mol Cell ; 76(1): 96-109.e9, 2019 10 03.

Artigo em Inglês | MEDLINE | ID: mdl-31474572

7.

A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations.

Singh, Amrita; Xue, Amy; Tai, Justin; Mbadugha, Faith; Obi, Prisca; Mascarenhas, Romario; Tyagi, Antariksh; Siena, Adamo; Chen, Y Grace.

RNA ; 2024 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-38485192

8.

LncRNA Seduction of GOT2 Goes Viral.

Chen, Y Grace; Chang, Howard Y.

Immunity ; 47(6): 1021-1023, 2017 12 19.

Artigo em Inglês | MEDLINE | ID: mdl-29262346

9.

Sensing Self and Foreign Circular RNAs by Intron Identity.

Chen, Y Grace; Kim, Myoungjoo V; Chen, Xingqi; Batista, Pedro J; Aoyama, Saeko; Wilusz, Jeremy E; Iwasaki, Akiko; Chang, Howard Y.

Mol Cell ; 67(2): 228-238.e5, 2017 Jul 20.

Artigo em Inglês | MEDLINE | ID: mdl-28625551

10.

Circular RNAs in Immune Response and Viral Infection.

Yan, Lichong; Chen, Y Grace.

Trends Biochem Sci ; 45(12): 1022-1034, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32900574

11.

m⁶A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.

Li, Hua-Bing; Tong, Jiyu; Zhu, Shu; Batista, Pedro J; Duffy, Erin E; Zhao, Jun; Bailis, Will; Cao, Guangchao; Kroehling, Lina; Chen, Yuanyuan; Wang, Geng; Broughton, James P; Chen, Y Grace; Kluger, Yuval; Simon, Matthew D; Chang, Howard Y; Yin, Zhinan; Flavell, Richard A.

Nature ; 548(7667): 338-342, 2017 08 17.

Artigo em Inglês | MEDLINE | ID: mdl-28792938

12.

The design and synthesis of circular RNAs.

Obi, Prisca; Chen, Y Grace.

Methods ; 196: 85-103, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-33662562

13.

Discovery and biological characterization of geranylated RNA in bacteria.

Dumelin, Christoph E; Chen, Yiyun; Leconte, Aaron M; Chen, Y Grace; Liu, David R.

Nat Chem Biol ; 8(11): 913-9, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22983156

14.

circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment.

Piras, Roberta; Ko, Emily Y; Barrett, Connor; De Simone, Marco; Lin, Xianzhi; Broz, Marina T; Tessaro, Fernando H G; Castillo-Martin, Mireia; Cordon-Cardo, Carlos; Goodridge, Helen S; Di Vizio, Dolores; Batish, Mona; Lawrenson, Kate; Chen, Y Grace; Chan, Keith Syson; Guarnerio, Jlenia.

Nat Commun ; 13(1): 7243, 2022 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-36433954

15.

Inflammasome activation in infected macrophages drives COVID-19 pathology.

Sefik, Esen; Qu, Rihao; Junqueira, Caroline; Kaffe, Eleanna; Mirza, Haris; Zhao, Jun; Brewer, J Richard; Han, Ailin; Steach, Holly R; Israelow, Benjamin; Blackburn, Holly N; Velazquez, Sofia; Chen, Y Grace; Halene, Stephanie; Iwasaki, Akiko; Meffre, Eric; Nussenzweig, Michel; Lieberman, Judy; Wilen, Craig B; Kluger, Yuval; Flavell, Richard A.

bioRxiv ; 2022 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-34611663

16.

LC/MS analysis of cellular RNA reveals NAD-linked RNA.

Chen, Y Grace; Kowtoniuk, Walter E; Agarwal, Isha; Shen, Yinghua; Liu, David R.

Nat Chem Biol ; 5(12): 879-81, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19820715

17.

Emerging roles of circular RNAs in innate immunity.

Li, Isabella; Chen, Y Grace.

Curr Opin Immunol ; 68: 107-115, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33176221

18.

Differences in the immunogenicity of engineered circular RNAs.

Tai, Justin; Chen, Y Grace.

J Mol Cell Biol ; 15(1)2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-36787893

19.

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.

Bailey, Alexis S; Batista, Pedro J; Gold, Rebecca S; Chen, Y Grace; de Rooij, Dirk G; Chang, Howard Y; Fuller, Margaret T.

Elife ; 62017 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-29087293

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One Ring to Rule Them All: Mitochondrial Circular RNAs Control Mitochondrial Function.

Cellular origins of dsRNA, their recognition and consequences.

Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.

Gene regulation in the immune system by long noncoding RNAs.

Inflammasome activation in infected macrophages drives COVID-19 pathology.

N6-Methyladenosine Modification Controls Circular RNA Immunity.

A scalable and cost-efficient rRNA depletion approach to enrich RNAs for molecular biology investigations.

LncRNA Seduction of GOT2 Goes Viral.

Sensing Self and Foreign Circular RNAs by Intron Identity.

Circular RNAs in Immune Response and Viral Infection.

m⁶A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways.

The design and synthesis of circular RNAs.

Discovery and biological characterization of geranylated RNA in bacteria.

circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment.

Inflammasome activation in infected macrophages drives COVID-19 pathology.

LC/MS analysis of cellular RNA reveals NAD-linked RNA.

Emerging roles of circular RNAs in innate immunity.

Differences in the immunogenicity of engineered circular RNAs.

The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline.