Detalhe da pesquisa
1.
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains.
EMBO J
; 43(11): 2166-2197, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600242
2.
Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition.
Cell
; 139(3): 560-72, 2009 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19879842
3.
High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2.
J Biol Chem
; 293(35): 13750-13765, 2018 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945974
4.
Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.
J Nat Prod
; 78(10): 2411-22, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26465675
5.
BLM overexpression as a predictive biomarker for CHK1 inhibitor response in PARP inhibitor-resistant BRCA-mutant ovarian cancer.
Sci Transl Med
; 15(701): eadd7872, 2023 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37343085
6.
Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery.
ACS Pharmacol Transl Sci
; 4(4): 1422-1436, 2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423274
7.
Regulation of MBK-2/Dyrk kinase by dynamic cortical anchoring during the oocyte-to-zygote transition.
Curr Biol
; 17(18): 1545-54, 2007 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17869113
8.
Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors.
ACS Comb Sci
; 22(8): 422-432, 2020 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32525297
9.
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay.
Elife
; 72018 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29528287
10.
Chemical genomics for studying parasite gene function and interaction.
Trends Parasitol
; 29(12): 603-11, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24215777
11.
A furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().
Medchemcomm
; 3(12): 1505-1511, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23205265
12.
Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.
ACS Med Chem Lett
; 3(2): 112-117, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22328964
13.
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.
Science
; 333(6043): 724-9, 2011 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21817045