Detalhe da pesquisa
1.
BRD4-PRC2 represses transcription of T-helper 2-specific negative regulators during T-cell differentiation.
EMBO J
; 42(6): e111473, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719036
2.
Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation.
Proc Natl Acad Sci U S A
; 121(18): e2312111121, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38657041
3.
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Mol Cell
; 65(6): 1068-1080.e5, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28262505
4.
HIPK2 directs cell type-specific regulation of STAT3 transcriptional activity in Th17 cell differentiation.
Proc Natl Acad Sci U S A
; 119(14): e2117112119, 2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35344430
5.
Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth.
Proc Natl Acad Sci U S A
; 115(31): 7949-7954, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012592
6.
The Ras GTPase-activating-like protein IQGAP1 mediates Nrf2 protein activation via the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)-ERK pathway.
J Biol Chem
; 288(31): 22378-86, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23788642
7.
Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation.
Mol Carcinog
; 53(1): 77-84, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22911891
8.
Structural mechanism of BRD4-NUT and p300 bipartite interaction in propagating aberrant gene transcription in chromatin in NUT carcinoma.
Nat Commun
; 14(1): 378, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36690674
9.
Phytochemicals: cancer chemoprevention and suppression of tumor onset and metastasis.
Cancer Metastasis Rev
; 29(3): 483-502, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20798979
10.
tBHQ-induced HO-1 expression is mediated by calcium through regulation of Nrf2 binding to enhancer and polymerase II to promoter region of HO-1.
Chem Res Toxicol
; 24(5): 670-6, 2011 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21443188
11.
The Functions of BET Proteins in Gene Transcription of Biology and Diseases.
Front Mol Biosci
; 8: 728777, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34540900
12.
Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM.
Carcinogenesis
; 31(5): 880-5, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19959557
13.
5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation.
Oncotarget
; 7(15): 19312-26, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27027355
14.
Pharmacogenetics, pharmacogenomics and epigenetics of Nrf2-regulated xenobiotic-metabolizing enzymes and transporters by dietary phytochemical and cancer chemoprevention.
Curr Drug Metab
; 14(6): 688-94, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23869812
15.
Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumors.
AAPS J
; 15(3): 864-74, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23658110
16.
PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.
Mol Cell Biol
; 32(8): 1506-17, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331464
17.
Epigenetic CpG demethylation of the promoter and reactivation of the expression of Neurog1 by curcumin in prostate LNCaP cells.
AAPS J
; 13(4): 606-14, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21938566
18.
Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention.
AAPS J
; 12(1): 87-97, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20013083
19.
Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.
PLoS One
; 5(1): e8579, 2010 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20062804
20.
Synergistic effect of combination of phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane in the inhibition of inflammation.
Pharm Res
; 26(1): 224-31, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18841446