Detalhe da pesquisa
1.
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Nature
; 616(7958): 755-763, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046083
2.
Genetic diversity fuels gene discovery for tobacco and alcohol use.
Nature
; 612(7941): 720-724, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477530
3.
Transcriptome-wide association study of the plasma proteome reveals cis and trans regulatory mechanisms underlying complex traits.
Am J Hum Genet
; 111(3): 445-455, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38320554
4.
Implications of Race Adjustment in Lung-Function Equations.
N Engl J Med
; 2024 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38767252
5.
Colocalization analysis of 3' UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function.
Hum Mol Genet
; 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569558
6.
The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells.
Am J Hum Genet
; 110(10): 1735-1749, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37734371
7.
A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases.
PLoS Genet
; 19(7): e1010825, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523391
8.
Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes.
PLoS Genet
; 19(6): e1010445, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37352370
9.
FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies.
Hum Mol Genet
; 32(4): 696-707, 2023 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36255742
10.
Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program.
Am J Hum Genet
; 109(5): 857-870, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35385699
11.
A statistical physics approach for disease module detection.
Genome Res
; 32(10): 1918-1929, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220609
12.
Variants in autophagy genes MTMR12 and FAM134A are putative modifiers of the hepatic phenotype in α1-antitrypsin deficiency.
Hepatology
; 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557779
13.
Genetically Predicted Body Mass Index and Mortality in COPD.
Am J Respir Crit Care Med
; 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471013
14.
Early Evidence of Chronic Obstructive Pulmonary Disease Obscured by Race-Specific Prediction Equations.
Am J Respir Crit Care Med
; 209(1): 59-69, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37611073
15.
A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables.
PLoS Genet
; 18(11): e1010464, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36383614
16.
Fast computation of the eigensystem of genomic similarity matrices.
BMC Bioinformatics
; 25(1): 43, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273228
17.
Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data.
Hum Mol Genet
; 31(22): 3873-3885, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35766891
18.
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.
Am J Hum Genet
; 108(10): 1836-1851, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34582791
19.
Genome-wide association study of preserved ratio impaired spirometry (PRISm).
Eur Respir J
; 63(1)2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38097206
20.
Association of clonal hematopoiesis with chronic obstructive pulmonary disease.
Blood
; 139(3): 357-368, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34855941