Detalhe da pesquisa
1.
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity.
Br J Cancer
; 123(4): 542-555, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439931
2.
The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model.
Int J Cancer
; 143(4): 992-1002, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29569717
3.
Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.
Br J Cancer
; 119(9): 1118-1128, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30377337
4.
Radiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18F-trifluoromethylation procedure.
Org Biomol Chem
; 16(16): 2986-2996, 2018 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29629716
5.
Molecular and metabolic consequences following E6 transfection in an isogenic ovarian cell line (A2780) pair.
Cell Physiol Biochem
; 32(5): 1460-72, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24296520
6.
¹H NMR and hyperpolarized ¹³C NMR assays of pyruvate-lactate: a comparative study.
NMR Biomed
; 26(10): 1321-1325, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23712817
7.
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.
Cancer Cell
; 8(2): 143-53, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16098467
8.
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
Hum Mol Genet
; 19(19): 3844-51, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20660115
9.
Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
BMC Cancer
; 11: 198, 2011 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21612605
10.
Corrigendum: VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.
Front Oncol
; 11: 740273, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34631576
11.
Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure.
J Mol Cell Cardiol
; 49(5): 851-63, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655923
12.
Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.
Circ Res
; 102(9): 1046-56, 2008 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18388323
13.
De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy.
Autophagy
; 16(6): 1044-1060, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31517566
14.
Glucose homeostasis across human airway epithelial cell monolayers: role of diffusion, transport and metabolism.
Pflugers Arch
; 457(5): 1061-70, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18781323
15.
Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies.
Cancer Chemother Pharmacol
; 61(3): 377-93, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17520257
16.
Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
Cancer Res
; 66(1): 427-34, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16397258
17.
VHL-Mediated Regulation of CHCHD4 and Mitochondrial Function.
Front Oncol
; 8: 388, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30338240
18.
Magnetic Resonance Spectroscopy (MRS)-Based Methods for Examining Cancer Metabolism in Response to Oncogenic Kinase Drug Treatment.
Methods Mol Biol
; 1636: 393-404, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28730493
19.
MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy.
Cancer Res
; 77(21): 5913-5924, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923861
20.
Evaluation of the combination of the dual m-TORC1/2 inhibitor vistusertib (AZD2014) and paclitaxel in ovarian cancer models.
Oncotarget
; 8(69): 113874-113884, 2017 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29371953