Detalhe da pesquisa
1.
Engineering a nanoantibiotic system displaying dual mechanism of action.
Proc Natl Acad Sci U S A
; 121(16): e2321498121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593077
2.
The structure of caseinolytic protease subunit ClpP2 reveals a functional model of the caseinolytic protease system from Chlamydia trachomatis.
J Biol Chem
; 299(1): 102762, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463962
3.
Structure-Activity Relationship Study to Develop Peptide Amphiphiles as Species-Specific Antimicrobials.
Chemistry
; 30(15): e202303986, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38221408
4.
Enhanced Hydrogen Bonding by Urea Functionalization Tunes the Stability and Biological Properties of Peptide Amphiphiles.
Biomacromolecules
; 25(5): 2823-2837, 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602228
5.
Evaluating the antimicrobial and anti-biofilm activity of three synthetic antimicrobial Citropin analogs and their ability to fight against Staphylococcus aureus and Staphylococcus pseudintermedius.
J Appl Microbiol
; 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38772746
6.
Synthesis and biological evaluation of sulfonylpyridine derivatives as potential anti-chlamydia agents.
Bioorg Med Chem
; 91: 117401, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37453189
7.
Designing peptide amphiphiles as novel antibacterials and antibiotic adjuvants against gram-negative bacteria.
Bioorg Med Chem
; 94: 117481, 2023 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37776750
8.
Pharmacophore modeling, molecular docking, and molecular dynamics studies to identify new 5-HT2AR antagonists with the potential for design of new atypical antipsychotics.
Mol Divers
; 27(5): 2217-2238, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409431
9.
Molecular Basis for the Morphological Transitions of Surfactant Wormlike Micelles Triggered by Encapsulated Nonpolar Molecules.
Langmuir
; 37(10): 3093-3103, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33683125
10.
Control of Peptide Amphiphile Supramolecular Nanostructures by Isosteric Replacements.
Biomacromolecules
; 22(8): 3274-3283, 2021 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34291897
11.
Initial Characterization of the Two ClpP Paralogs of Chlamydia trachomatis Suggests Unique Functionality for Each.
J Bacteriol
; 201(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30396899
12.
A review of the molecular design and biological activities of RXR agonists.
Med Res Rev
; 39(4): 1372-1397, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30941786
13.
Design and synthesis of new piperidone grafted acetylcholinesterase inhibitors.
Bioorg Med Chem Lett
; 27(2): 228-231, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27914796
14.
Erratum for Wood et al., "Initial Characterization of the Two ClpP Paralogs of Chlamydia trachomatis Suggests Unique Functionality for Each".
J Bacteriol
; 201(24)2019 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748407
15.
Editorial page, special issue honoring Professor Mark Cushman.
Med Res Rev
; 39(4): 1233-1234, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31194276
16.
De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain.
RSC Med Chem
; 14(9): 1722-1733, 2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37731704
17.
Design, Biological Evaluation, and Computer-Aided Analysis of Dihydrothiazepines as Selective Antichlamydial Agents.
J Med Chem
; 66(3): 2116-2142, 2023 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696579
18.
Induction of apoptosis by 3-amino-6-(3-aminopropyl)-5,6-dihydro-5,11-dioxo-11H-indeno[1,2-c]isoquinoline via modulation of MAPKs (p38 and c-Jun N-terminal kinase) and c-Myc in HL-60 human leukemia cells.
J Nat Prod
; 75(3): 378-84, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22148260
19.
In Vitro and In Vivo Activity of (Trifluoromethyl)pyridines as Anti-Chlamydia trachomatis Agents.
ACS Infect Dis
; 8(1): 227-241, 2022 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935346
20.
Urea-Modified Self-Assembling Peptide Amphiphiles That Form Well-Defined Nanostructures and Hydrogels for Biomedical Applications.
ACS Appl Bio Mater
; 5(10): 4599-4610, 2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653507