Detalhe da pesquisa
1.
BMP7-induced-Pten inhibits Akt and prevents renal fibrosis.
Biochim Biophys Acta Mol Basis Dis
; 1863(12): 3095-3104, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923783
2.
Discovery of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
Bioorg Med Chem Lett
; 24(3): 949-53, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24412066
3.
Discovery of camphor-derived pyrazolones as 11ß-hydroxysteroid dehydrogenase type 1 inhibitors.
Bioorg Med Chem Lett
; 24(12): 2707-11, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24815509
4.
Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension.
Bioconjug Chem
; 24(12): 2015-24, 2013 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24251972
5.
Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.
Bioorg Med Chem Lett
; 23(10): 2936-40, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23582275
6.
Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists.
Bioorg Med Chem Lett
; 23(16): 4627-32, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23831134
7.
Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs.
Bioorg Med Chem Lett
; 23(14): 4216-20, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23743277
8.
Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture.
J Am Coll Cardiol
; 81(23): 2213-2227, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286250
9.
Discovery of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as glutamine fructose-6-phosphate amidotransferase (GFAT) inhibitors.
Bioorg Med Chem Lett
; 21(21): 6264-9, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21958546
10.
Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.
Bioorg Med Chem Lett
; 21(23): 7205-9, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001092
11.
Autotaxin Inhibitor Protects from Chronic Allograft Injury in Rat Kidney Allotransplantation.
Nephron
; 144(1): 38-48, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31550726
12.
A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?
Atherosclerosis
; 314: 1-9, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33129080
13.
Potent, selective MCH-1 receptor antagonists.
Bioorg Med Chem Lett
; 18(4): 1402-6, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18243691
14.
Incretin-like effects of small molecule trace amine-associated receptor 1 agonists.
Mol Metab
; 5(1): 47-56, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26844206
15.
The common insertional polymorphism in the APOC1 promoter is associated with serum apolipoprotein C-I levels in Hispanic children.
Atherosclerosis
; 179(2): 387-93, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15777558
16.
A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.
Nat Med
; 21(1): 27-36, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25485909
17.
Sex and hormonal status influence the effects of psyllium on lipoprotein remodeling and composition.
Metabolism
; 51(4): 500-7, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11912561
18.
Beneficial effects of weight loss on plasma apolipoproteins in postmenopausal women.
J Nutr Biochem
; 15(12): 717-21, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15607644
19.
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor ß agonist in clinical trials for the treatment of dyslipidemia.
J Med Chem
; 57(10): 3912-23, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24712661
20.
PK modulation of haptenylated peptides via non-covalent antibody complexation.
J Control Release
; 171(1): 48-56, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23800420