Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

Gurdasani, Deepti; Carstensen, Tommy; Fatumo, Segun; Chen, Guanjie; Franklin, Chris S; Prado-Martinez, Javier; Bouman, Heleen; Abascal, Federico; Haber, Marc; Tachmazidou, Ioanna; Mathieson, Iain; Ekoru, Kenneth; DeGorter, Marianne K; Nsubuga, Rebecca N; Finan, Chris; Wheeler, Eleanor; Chen, Li; Cooper, David N; Schiffels, Stephan; Chen, Yuan; Ritchie, Graham R S; Pollard, Martin O; Fortune, Mary D; Mentzer, Alex J; Garrison, Erik; Bergström, Anders; Hatzikotoulas, Konstantinos; Adeyemo, Adebowale; Doumatey, Ayo; Elding, Heather; Wain, Louise V; Ehret, Georg; Auer, Paul L; Kooperberg, Charles L; Reiner, Alexander P; Franceschini, Nora; Maher, Dermot; Montgomery, Stephen B; Kadie, Carl; Widmer, Chris; Xue, Yali; Seeley, Janet; Asiki, Gershim; Kamali, Anatoli; Young, Elizabeth H; Pomilla, Cristina; Soranzo, Nicole; Zeggini, Eleftheria; Pirie, Fraser; Morris, Andrew P.

Cell ; 179(4): 984-1002.e36, 2019 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-31675503

2.

BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants.

Liu, Jianying; Liu, Yang; Xia, Hongjie; Zou, Jing; Weaver, Scott C; Swanson, Kena A; Cai, Hui; Cutler, Mark; Cooper, David; Muik, Alexander; Jansen, Kathrin U; Sahin, Ugur; Xie, Xuping; Dormitzer, Philip R; Shi, Pei-Yong.

Nature ; 596(7871): 273-275, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34111888

3.

BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.

Sahin, Ugur; Muik, Alexander; Vogler, Isabel; Derhovanessian, Evelyna; Kranz, Lena M; Vormehr, Mathias; Quandt, Jasmin; Bidmon, Nicole; Ulges, Alexander; Baum, Alina; Pascal, Kristen E; Maurus, Daniel; Brachtendorf, Sebastian; Lörks, Verena; Sikorski, Julian; Koch, Peter; Hilker, Rolf; Becker, Dirk; Eller, Ann-Kathrin; Grützner, Jan; Tonigold, Manuel; Boesler, Carsten; Rosenbaum, Corinna; Heesen, Ludwig; Kühnle, Marie-Cristine; Poran, Asaf; Dong, Jesse Z; Luxemburger, Ulrich; Kemmer-Brück, Alexandra; Langer, David; Bexon, Martin; Bolte, Stefanie; Palanche, Tania; Schultz, Armin; Baumann, Sybille; Mahiny, Azita J; Boros, Gábor; Reinholz, Jonas; Szabó, Gábor T; Karikó, Katalin; Shi, Pei-Yong; Fontes-Garfias, Camila; Perez, John L; Cutler, Mark; Cooper, David; Kyratsous, Christos A; Dormitzer, Philip R; Jansen, Kathrin U; Türeci, Özlem.

Nature ; 595(7868): 572-577, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34044428

4.

Bivalent Omicron BA.1-Adapted BNT162b2 Booster in Adults Older than 55 Years.

Winokur, Patricia; Gayed, Juleen; Fitz-Patrick, David; Thomas, Stephen J; Diya, Oyeniyi; Lockhart, Stephen; Xu, Xia; Zhang, Ying; Bangad, Vishva; Schwartz, Howard I; Denham, Douglas; Cardona, Jose F; Usdan, Lisa; Ginis, John; Mensa, Federico J; Zou, Jing; Xie, Xuping; Shi, Pei-Yong; Lu, Claire; Buitrago, Sandra; Scully, Ingrid L; Cooper, David; Koury, Kenneth; Jansen, Kathrin U; Türeci, Özlem; Sahin, Ugur; Swanson, Kena A; Gruber, William C; Kitchin, Nicholas.

N Engl J Med ; 388(3): 214-227, 2023 01 19.

Artigo em Inglês | MEDLINE | ID: mdl-36652353

5.

Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults.

Walsh, Edward E; Pérez Marc, Gonzalo; Zareba, Agnieszka M; Falsey, Ann R; Jiang, Qin; Patton, Michael; Polack, Fernando P; Llapur, Conrado; Doreski, Pablo A; Ilangovan, Kumar; Rämet, Mika; Fukushima, Yasushi; Hussen, Nazreen; Bont, Louis J; Cardona, Jose; DeHaan, Elliot; Castillo Villa, Giselle; Ingilizova, Marinela; Eiras, Daniel; Mikati, Tarek; Shah, Rupal N; Schneider, Katherine; Cooper, David; Koury, Kenneth; Lino, Maria-Maddalena; Anderson, Annaliesa S; Jansen, Kathrin U; Swanson, Kena A; Gurtman, Alejandra; Gruber, William C; Schmoele-Thoma, Beate.

N Engl J Med ; 388(16): 1465-1477, 2023 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-37018468

6.

Evaluation of BNT162b2 Covid-19 Vaccine in Children Younger than 5 Years of Age.

Muñoz, Flor M; Sher, Lawrence D; Sabharwal, Charu; Gurtman, Alejandra; Xu, Xia; Kitchin, Nicholas; Lockhart, Stephen; Riesenberg, Robert; Sexter, Joanna M; Czajka, Hanna; Paulsen, Grant C; Maldonado, Yvonne; Walter, Emmanuel B; Talaat, Kawsar R; Englund, Janet A; Sarwar, Uzma N; Hansen, Caitlin; Iwamoto, Martha; Webber, Chris; Cunliffe, Luke; Ukkonen, Benita; Martínez, Silvina N; Pahud, Barbara A; Munjal, Iona; Domachowske, Joseph B; Swanson, Kena A; Ma, Hua; Koury, Kenneth; Mather, Susan; Lu, Claire; Zou, Jing; Xie, Xuping; Shi, Pei-Yong; Cooper, David; Türeci, Özlem; Sahin, Ugur; Jansen, Kathrin U; Gruber, William C.

N Engl J Med ; 388(7): 621-634, 2023 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-36791162

7.

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants.

Kampmann, Beate; Madhi, Shabir A; Munjal, Iona; Simões, Eric A F; Pahud, Barbara A; Llapur, Conrado; Baker, Jeffrey; Pérez Marc, Gonzalo; Radley, David; Shittu, Emma; Glanternik, Julia; Snaggs, Hasra; Baber, James; Zachariah, Philip; Barnabas, Shaun L; Fausett, Merlin; Adam, Tyler; Perreras, Nicole; Van Houten, Marlies A; Kantele, Anu; Huang, Li-Min; Bont, Louis J; Otsuki, Takeo; Vargas, Sergio L; Gullam, Joanna; Tapiero, Bruce; Stein, Renato T; Polack, Fernando P; Zar, Heather J; Staerke, Nina B; Duron Padilla, María; Richmond, Peter C; Koury, Kenneth; Schneider, Katherine; Kalinina, Elena V; Cooper, David; Jansen, Kathrin U; Anderson, Annaliesa S; Swanson, Kena A; Gruber, William C; Gurtman, Alejandra.

N Engl J Med ; 388(16): 1451-1464, 2023 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-37018474

8.

Gene Therapy with Etranacogene Dezaparvovec for Hemophilia B.

Pipe, Steven W; Leebeek, Frank W G; Recht, Michael; Key, Nigel S; Castaman, Giancarlo; Miesbach, Wolfgang; Lattimore, Susan; Peerlinck, Kathelijne; Van der Valk, Paul; Coppens, Michiel; Kampmann, Peter; Meijer, Karina; O'Connell, Niamh; Pasi, K John; Hart, Daniel P; Kazmi, Rashid; Astermark, Jan; Hermans, Cedric R J R; Klamroth, Robert; Lemons, Richard; Visweshwar, Nathan; von Drygalski, Annette; Young, Guy; Crary, Shelley E; Escobar, Miguel; Gomez, Esteban; Kruse-Jarres, Rebecca; Quon, Doris V; Symington, Emily; Wang, Michael; Wheeler, Allison P; Gut, Robert; Liu, Ying P; Dolmetsch, Ricardo E; Cooper, David L; Li, Yanyan; Goldstein, Brahm; Monahan, Paul E.

N Engl J Med ; 388(8): 706-718, 2023 02 23.

Artigo em Inglês | MEDLINE | ID: mdl-36812434

9.

Global priority areas for ecosystem restoration.

Strassburg, Bernardo B N; Iribarrem, Alvaro; Beyer, Hawthorne L; Cordeiro, Carlos Leandro; Crouzeilles, Renato; Jakovac, Catarina C; Braga Junqueira, André; Lacerda, Eduardo; Latawiec, Agnieszka E; Balmford, Andrew; Brooks, Thomas M; Butchart, Stuart H M; Chazdon, Robin L; Erb, Karl-Heinz; Brancalion, Pedro; Buchanan, Graeme; Cooper, David; Díaz, Sandra; Donald, Paul F; Kapos, Valerie; Leclère, David; Miles, Lera; Obersteiner, Michael; Plutzar, Christoph; de M Scaramuzza, Carlos Alberto; Scarano, Fabio R; Visconti, Piero.

Nature ; 586(7831): 724-729, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-33057198

10.

Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults.

Mulligan, Mark J; Lyke, Kirsten E; Kitchin, Nicholas; Absalon, Judith; Gurtman, Alejandra; Lockhart, Stephen; Neuzil, Kathleen; Raabe, Vanessa; Bailey, Ruth; Swanson, Kena A; Li, Ping; Koury, Kenneth; Kalina, Warren; Cooper, David; Fontes-Garfias, Camila; Shi, Pei-Yong; Türeci, Özlem; Tompkins, Kristin R; Walsh, Edward E; Frenck, Robert; Falsey, Ann R; Dormitzer, Philip R; Gruber, William C; Sahin, Ugur; Jansen, Kathrin U.

Nature ; 586(7830): 589-593, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32785213

11.

COVID-19 vaccine BNT162b1 elicits human antibody and T_H1 T cell responses.

Sahin, Ugur; Muik, Alexander; Derhovanessian, Evelyna; Vogler, Isabel; Kranz, Lena M; Vormehr, Mathias; Baum, Alina; Pascal, Kristen; Quandt, Jasmin; Maurus, Daniel; Brachtendorf, Sebastian; Lörks, Verena; Sikorski, Julian; Hilker, Rolf; Becker, Dirk; Eller, Ann-Kathrin; Grützner, Jan; Boesler, Carsten; Rosenbaum, Corinna; Kühnle, Marie-Cristine; Luxemburger, Ulrich; Kemmer-Brück, Alexandra; Langer, David; Bexon, Martin; Bolte, Stefanie; Karikó, Katalin; Palanche, Tania; Fischer, Boris; Schultz, Armin; Shi, Pei-Yong; Fontes-Garfias, Camila; Perez, John L; Swanson, Kena A; Loschko, Jakob; Scully, Ingrid L; Cutler, Mark; Kalina, Warren; Kyratsous, Christos A; Cooper, David; Dormitzer, Philip R; Jansen, Kathrin U; Türeci, Özlem.

Nature ; 586(7830): 594-599, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32998157

12.

A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system.

Belgrad, Jillian; Tang, Qi; Hildebrand, Sam; Summers, Ashley; Sapp, Ellen; Echeverria, Dimas; O'Reilly, Dan; Luu, Eric; Bramato, Brianna; Allen, Sarah; Cooper, David; Alterman, Julia; Yamada, Ken; Aronin, Neil; DiFiglia, Marian; Khvorova, Anastasia.

Nucleic Acids Res ; 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38726879

13.

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo.

Zhang, Han; Kelly, Karen; Lee, Jonathan; Echeverria, Dimas; Cooper, David; Panwala, Rebecca; Amrani, Nadia; Chen, Zexiang; Gaston, Nicholas; Wagh, Atish; Newby, Gregory A; Xie, Jun; Liu, David R; Gao, Guangping; Wolfe, Scot A; Khvorova, Anastasia; Watts, Jonathan K; Sontheimer, Erik J.

Nucleic Acids Res ; 52(2): 977-997, 2024 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-38033325

14.

Genome-wide detection of human intronic AG-gain variants located between splicing branchpoints and canonical splice acceptor sites.

Zhang, Peng; Chaldebas, Matthieu; Ogishi, Masato; Al Qureshah, Fahd; Ponsin, Khoren; Feng, Yi; Rinchai, Darawan; Milisavljevic, Baptiste; Han, Ji Eun; Moncada-Vélez, Marcela; Keles, Sevgi; Schröder, Bernd; Stenson, Peter D; Cooper, David N; Cobat, Aurélie; Boisson, Bertrand; Zhang, Qian; Boisson-Dupuis, Stéphanie; Abel, Laurent; Casanova, Jean-Laurent.

Proc Natl Acad Sci U S A ; 120(46): e2314225120, 2023 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-37931111

15.

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.

Hariharan, Vignesh N; Shin, Minwook; Chang, Ching-Wen; O'Reilly, Daniel; Biscans, Annabelle; Yamada, Ken; Guo, Zhiru; Somasundaran, Mohan; Tang, Qi; Monopoli, Kathryn; Krishnamurthy, Pranathi Meda; Devi, Gitali; McHugh, Nicholas; Cooper, David A; Echeverria, Dimas; Cruz, John; Chan, Io Long; Liu, Ping; Lim, Sun-Young; McConnell, Jill; Singh, Satya Prakash; Hildebrand, Samuel; Sousa, Jacquelyn; Davis, Sarah M; Kennedy, Zachary; Ferguson, Chantal; Godinho, Bruno M D C; Thillier, Yann; Caiazzi, Jillian; Ly, Socheata; Muhuri, Manish; Kelly, Karen; Humphries, Fiachra; Cousineau, Alyssa; Parsi, Krishna Mohan; Li, Qi; Wang, Yang; Maehr, René; Gao, Guangping; Korkin, Dmitry; McDougall, William M; Finberg, Robert W; Fitzgerald, Katherine A; Wang, Jennifer P; Watts, Jonathan K; Khvorova, Anastasia.

Proc Natl Acad Sci U S A ; 120(11): e2219523120, 2023 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-36893269

16.

Deciphering the Role of Rapidly Evolving Conserved Elements in Primate Brain Development and Exploring Their Potential Involvement in Alzheimer's Disease.

Hu, Benxia; Zhuang, Xiao-Lin; Zhou, Long; Zhang, Guojie; Cooper, David N; Wu, Dong-Dong.

Mol Biol Evol ; 41(1)2024 Jan 03.

Artigo em Inglês | MEDLINE | ID: mdl-38175672

17.

Genome-wide identification of dominant polyadenylation hexamers for use in variant classification.

Shiferaw, Henoke K; Hong, Celine S; Cooper, David N; Johnston, Jennifer J; Biesecker, Leslie G.

Hum Mol Genet ; 32(23): 3211-3224, 2023 Nov 17.

Artigo em Inglês | MEDLINE | ID: mdl-37606238

18.

Analysis of missense variants in the human genome reveals widespread gene-specific clustering and improves prediction of pathogenicity.

Quinodoz, Mathieu; Peter, Virginie G; Cisarova, Katarina; Royer-Bertrand, Beryl; Stenson, Peter D; Cooper, David N; Unger, Sheila; Superti-Furga, Andrea; Rivolta, Carlo.

Am J Hum Genet ; 109(3): 457-470, 2022 03 03.

Artigo em Inglês | MEDLINE | ID: mdl-35120630

19.

Hyperthyroidism.

Chaker, Layal; Cooper, David S; Walsh, John P; Peeters, Robin P.

Lancet ; 403(10428): 768-780, 2024 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-38278171

20.

Single-Incision Mini-Slings for Stress Urinary Incontinence in Women.

Abdel-Fattah, Mohamed; Cooper, David; Davidson, Tracey; Kilonzo, Mary; Hossain, Md; Boyers, Dwayne; Bhal, Kiron; Wardle, Judith; N'Dow, James; MacLennan, Graeme; Norrie, John.

N Engl J Med ; 386(13): 1230-1243, 2022 03 31.

Artigo em Inglês | MEDLINE | ID: mdl-35353961

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