Detalhe da pesquisa
1.
Current directions in tau research: Highlights from Tau 2020.
Alzheimers Dement
; 18(5): 988-1007, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34581500
2.
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity.
EMBO J
; 34(24): 3028-41, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26538322
3.
Tau reduction in the presence of amyloid-ß prevents tau pathology and neuronal death in vivo.
Brain
; 141(7): 2194-2212, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733334
4.
The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease.
J Neuroinflammation
; 15(1): 269, 2018 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30227881
5.
Enhanced Tau Aggregation in the Presence of Amyloid ß.
Am J Pathol
; 187(7): 1601-1612, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500862
6.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Am J Pathol
; 187(6): 1399-1412, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28408124
7.
Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies.
Ann Neurol
; 81(1): 117-128, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27997036
8.
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Ann Neurol
; 80(3): 355-67, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27351289
9.
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds.
Proc Natl Acad Sci U S A
; 110(33): E3138-47, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898162
10.
Antisense reduction of tau in adult mice protects against seizures.
J Neurosci
; 33(31): 12887-97, 2013 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23904623
11.
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia.
Trends Cell Biol
; 33(4): 324-339, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36244875
12.
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system.
Prog Neurobiol
; 208: 102181, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34670118
13.
Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Mol Neurodegener
; 17(1): 41, 2022 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35690868
14.
In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease.
Sci Adv
; 7(44): eabh1448, 2021 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34714685
15.
Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.
Sci Adv
; 7(12)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33741591
16.
Transcriptional coactivators are not required for herpes simplex virus type 1 immediate-early gene expression in vitro.
J Virol
; 83(8): 3436-49, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19176620
17.
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.
Sci Transl Med
; 12(545)2020 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461332
18.
Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain.
Front Neurosci
; 12: 267, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29740275
19.
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.
Neuron
; 99(5): 925-940.e7, 2018 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30189209
20.
Tau at the Crossroads between Neurotoxicity and Neuroprotection.
Neuron
; 94(4): 703-704, 2017 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28521124