Detalhe da pesquisa
1.
Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase.
Cell
; 167(2): 498-511.e14, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693351
2.
Rapid excision of oxidized adenine by human thymine DNA glycosylase.
J Biol Chem
; 299(1): 102756, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460098
3.
Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase.
Nucleic Acids Res
; 46(10): 5159-5170, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29660017
4.
Defining the Role of Nucleotide Flipping in Enzyme Specificity Using 19F NMR.
J Am Chem Soc
; 141(12): 4952-4962, 2019 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30841696
5.
Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J Am Chem Soc
; 141(47): 18851-18861, 2019 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31693361
6.
Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNA.
Chem Rev
; 116(20): 12711-12729, 2016 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27501078
7.
Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res
; 44(21): 10248-10258, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580719
8.
Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo.
J Biol Chem
; 291(17): 9014-24, 2016 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917720
9.
Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging.
Nucleic Acids Res
; 43(5): 2716-29, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25712093
10.
Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res
; 43(19): 9541-52, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26358812
11.
Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
Biochemistry
; 55(45): 6205-6208, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27805810
12.
E2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex.
J Biol Chem
; 289(22): 15810-9, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24753249
13.
Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc Natl Acad Sci U S A
; 109(21): 8091-6, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22573813
14.
Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA.
Org Biomol Chem
; 12(42): 8367-78, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25181003
15.
Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 12): 2555-62, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311596
16.
Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.
J Am Chem Soc
; 135(42): 15813-22, 2013 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24063363
17.
Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA.
Nucleic Acids Res
; 39(6): 2319-29, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21097883
18.
Characterizing inhibitors of human AP endonuclease 1.
PLoS One
; 18(1): e0280526, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652434
19.
Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.
bioRxiv
; 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37873231
20.
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites.
J Biol Chem
; 286(41): 35334-35338, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21862836