Detalhe da pesquisa
1.
Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.
Nature
; 578(7793): 160-165, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969707
2.
Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
J Virol
; 96(7): e0169921, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35293766
3.
CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
J Virol
; 95(8)2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568515
4.
SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.
J Virol
; 94(21)2020 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817214
5.
Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid.
J Immunol
; 190(5): 2009-16, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359509
6.
Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques.
J Virol
; 86(2): 1203-13, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22090099
7.
Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques.
PLoS Pathog
; 7(5): e1002048, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21625590
8.
AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
Nat Med
; 29(10): 2535-2546, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783968
9.
IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health.
JCI Insight
; 7(5)2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35104248
10.
Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
J Clin Invest
; 132(8)2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35426377
11.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
J Clin Invest
; 118(6): 2039-49, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18497876
12.
Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway.
Hepatology
; 51(5): 1584-92, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20225248
13.
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.
Blood
; 113(25): 6304-14, 2009 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19380868
14.
Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.
J Immunol
; 183(1): 706-17, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19542473
15.
DNA-Encoded Library Technology-Based Discovery, Lead Optimization, and Prodrug Strategy toward Structurally Unique Indoleamine 2,3-Dioxygenase-1 (IDO1) Inhibitors.
J Med Chem
; 63(7): 3552-3562, 2020 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32073266
16.
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
J Virol
; 82(7): 3725-35, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18216113
17.
Gut epithelial barrier and systemic inflammation during chronic HIV infection.
AIDS
; 29(1): 43-51, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25387317
18.
Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques.
Cell Rep
; 13(8): 1589-97, 2015 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586432
19.
Discordance between peripheral and colonic markers of inflammation during suppressive ART.
J Acquir Immune Defic Syndr
; 65(2): 133-41, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121758
20.
The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4+ T cell recovery: a randomized crossover trial.
PLoS One
; 9(12): e116306, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25545673