Detalhe da pesquisa
1.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922586
2.
Safety, Tolerability, and Pharmacokinetics of JNJ-1802, a Pan-serotype Dengue Direct Antiviral Small Molecule, in a Phase 1, Double-Blind, Randomized, Dose-Escalation Study in Healthy Volunteers.
Clin Infect Dis
; 77(6): 857-865, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37161721
3.
Efficacy of Long-Acting Bedaquiline Regimens in a Mouse Model of Tuberculosis Preventive Therapy.
Am J Respir Crit Care Med
; 205(5): 570-579, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34939891
4.
Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study).
Genet Med
; 24(10): 2004-2013, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35951014
5.
Repellent activity against Anopheles gambiae of the leaves of nesting trees in the Sebitoli chimpanzee community of Kibale National Park, Uganda.
Malar J
; 21(1): 271, 2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36163024
6.
Exacerbation of Background Nuclear Cataracts in Sprague-Dawley Rats in Embryo-Fetal Development Studies With JNJ-42165279, a Fatty Acid Amide Hydrolase Inhibitor.
Toxicol Pathol
; 49(6): 1193-1205, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34128434
7.
Thyroid hormone and folinic acid in young children with Down syndrome: the phase 3 ACTHYF trial.
Genet Med
; 22(1): 44-52, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31281181
8.
Activity of a Long-Acting Injectable Bedaquiline Formulation in a Paucibacillary Mouse Model of Latent Tuberculosis Infection.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745396
9.
Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission.
PLoS Pathog
; 11(8): e1005075, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26271040
10.
Chimpanzees select comfortable nesting tree species.
Sci Rep
; 13(1): 16943, 2023 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37805595
11.
DNA methylation profiling in Trisomy 21 females with and without breast cancer.
Front Oncol
; 13: 1203483, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37538118
12.
Correction: Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission.
PLoS Pathog
; 11(10): e1005170, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474397
13.
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Bioorg Med Chem Lett
; 22(9): 3265-8, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22472694
14.
DYRK1A and Activity-Dependent Neuroprotective Protein Comparative Diagnosis Interest in Cerebrospinal Fluid and Plasma in the Context of Alzheimer-Related Cognitive Impairment in Down Syndrome Patients.
Biomedicines
; 10(6)2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35740400
15.
Antiviral activity and mode of action of TMC647078, a novel nucleoside inhibitor of the hepatitis C virus NS5B polymerase.
Antimicrob Agents Chemother
; 55(8): 3812-20, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21576430
16.
Opportunities, barriers, and recommendations in down syndrome research.
Transl Sci Rare Dis
; 5(3-4): 99-129, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34268067
17.
Transcriptomic study in women with trisomy 21 identifies a possible role of the GTPases of the immunity-associated proteins (GIMAP) in the protection of breast cancer.
Sci Rep
; 10(1): 9447, 2020 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32523132
18.
Absorption, metabolism, and excretion of darunavir, a new protease inhibitor, administered alone and with low-dose ritonavir in healthy subjects.
Drug Metab Dispos
; 37(4): 809-20, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19131522
19.
The walnut genetic resources of INRA: chronological phenotypic data and ontology.
BMC Res Notes
; 12(1): 662, 2019 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31623654
20.
Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and risk/benefit to patients.
PLoS Negl Trop Dis
; 13(1): e0007026, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30650076