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1.

Disparities in acute myeloid leukemia treatments and outcomes.

Eisfeld, Ann-Kathrin.

Curr Opin Hematol ; 31(2): 58-63, 2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-38059809

2.

DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.

Giacopelli, Brian; Wang, Min; Cleary, Ada; Wu, Yue-Zhong; Schultz, Anna Reister; Schmutz, Maximilian; Blachly, James S; Eisfeld, Ann-Kathrin; Mundy-Bosse, Bethany; Vosberg, Sebastian; Greif, Philipp A; Claus, Rainer; Bullinger, Lars; Garzon, Ramiro; Coombes, Kevin R; Bloomfield, Clara D; Druker, Brian J; Tyner, Jeffrey W; Byrd, John C; Oakes, Christopher C.

Genome Res ; 31(5): 747-761, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33707228

3.

High-dimensional genomic feature selection with the ordered stereotype logit model.

Seffernick, Anna Eames; Mrózek, Krzysztof; Nicolet, Deedra; Stone, Richard M; Eisfeld, Ann-Kathrin; Byrd, John C; Archer, Kellie J.

Brief Bioinform ; 23(6)2022 11 19.

Artigo em Inglês | MEDLINE | ID: mdl-36184192

4.

Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.

Ferraro, Francesca; Miller, Christopher A; Christensen, Keegan A; Helton, Nichole M; O'Laughlin, Margaret; Fronick, Catrina C; Fulton, Robert S; Kohlschmidt, Jessica; Eisfeld, Ann-Kathrin; Bloomfield, Clara D; Ramakrishnan, Sai Mukund; Day, Ryan B; Wartman, Lukas D; Uy, Geoffrey L; Welch, John S; Christopher, Matthew J; Heath, Sharon E; Baty, Jack D; Schuelke, Matthew J; Payton, Jacqueline E; Spencer, David H; Rettig, Michael P; Link, Daniel C; Walter, Matthew J; Westervelt, Peter; DiPersio, John F; Ley, Timothy J.

Proc Natl Acad Sci U S A ; 118(49)2021 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-34845035

5.

Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.

Bill, Marius; Mrózek, Krzysztof; Kohlschmidt, Jessica; Eisfeld, Ann-Kathrin; Walker, Christopher J; Nicolet, Deedra; Papaioannou, Dimitrios; Blachly, James S; Orwick, Shelley; Carroll, Andrew J; Kolitz, Jonathan E; Powell, Bayard L; Stone, Richard M; de la Chapelle, Albert; Byrd, John C; Bloomfield, Clara D.

Proc Natl Acad Sci U S A ; 117(42): 26340-26346, 2020 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-33020282

6.

Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.

Papaioannou, Dimitrios; Ozer, Hatice G; Nicolet, Deedra; Urs, Amog P; Herold, Tobias; Mrózek, Krzysztof; Batcha, Aarif M N; Metzeler, Klaus H; Yilmaz, Ayse S; Volinia, Stefano; Bill, Marius; Kohlschmidt, Jessica; Pietrzak, Maciej; Walker, Christopher J; Carroll, Andrew J; Braess, Jan; Powell, Bayard L; Eisfeld, Ann-Kathrin; Uy, Geoffrey L; Wang, Eunice S; Kolitz, Jonathan E; Stone, Richard M; Hiddemann, Wolfgang; Byrd, John C; Bloomfield, Clara D; Garzon, Ramiro.

Haematologica ; 107(5): 1034-1044, 2022 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-34261293

7.

Controlled variable selection in Weibull mixture cure models for high-dimensional data.

Fu, Han; Nicolet, Deedra; Mrózek, Krzysztof; Stone, Richard M; Eisfeld, Ann-Kathrin; Byrd, John C; Archer, Kellie J.

Stat Med ; 41(22): 4340-4366, 2022 09 30.

Artigo em Inglês | MEDLINE | ID: mdl-35792553

8.

Discovery of clinically relevant fusions in pediatric cancer.

LaHaye, Stephanie; Fitch, James R; Voytovich, Kyle J; Herman, Adam C; Kelly, Benjamin J; Lammi, Grant E; Arbesfeld, Jeremy A; Wijeratne, Saranga; Franklin, Samuel J; Schieffer, Kathleen M; Bir, Natalie; McGrath, Sean D; Miller, Anthony R; Wetzel, Amy; Miller, Katherine E; Bedrosian, Tracy A; Leraas, Kristen; Varga, Elizabeth A; Lee, Kristy; Gupta, Ajay; Setty, Bhuvana; Boué, Daniel R; Leonard, Jeffrey R; Finlay, Jonathan L; Abdelbaki, Mohamed S; Osorio, Diana S; Koo, Selene C; Koboldt, Daniel C; Wagner, Alex H; Eisfeld, Ann-Kathrin; Mrózek, Krzysztof; Magrini, Vincent; Cottrell, Catherine E; Mardis, Elaine R; Wilson, Richard K; White, Peter.

BMC Genomics ; 22(1): 872, 2021 Dec 04.

Artigo em Inglês | MEDLINE | ID: mdl-34863095

9.

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia.

Bill, Marius; Nicolet, Deedra; Kohlschmidt, Jessica; Walker, Christopher J; Mrózek, Krzysztof; Eisfeld, Ann-Kathrin; Papaioannou, Dimitrios; Rong-Mullins, Xiaoqing; Brannan, Zachary; Kolitz, Jonathan E; Powell, Bayard L; Archer, Kellie J; Dorrance, Adrienne M; Carroll, Andrew J; Stone, Richard M; Byrd, John C; Garzon, Ramiro; Bloomfield, Clara D.

Haematologica ; 105(3): 721-729, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31413100

10.

Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.

Duggan, Megan C; Stiff, Andrew R; Bainazar, Maryam; Regan, Kelly; Olaverria Salavaggione, Gonzalo N; Maharry, Sophia; Blachly, James S; Krischak, Madison; Walker, Christopher J; Latchana, Nicholas; Tridandapani, Susheela; de la Chapelle, Albert; Eisfeld, Ann-Kathrin; Carson, William E.

Proc Natl Acad Sci U S A ; 114(36): 9629-9634, 2017 09 05.

Artigo em Inglês | MEDLINE | ID: mdl-28827320

11.

Acute Myeloid Leukemia Genomics: Impact on Care and Remaining Challenges.

Eisfeld, Ann-Kathrin; Mardis, Elaine R.

Clin Chem ; 70(1): 4-12, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38175584

12.

Unbiased decision-making for acute myeloid leukemia still needed.

Eisfeld, Ann-Kathrin.

Haematologica ; 108(3): 668-669, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-35708138

13.

MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies.

Lankenau, Malori A; Patel, Ravi; Liyanarachchi, Sandya; Maharry, Sophia E; Hoag, Kevin W; Duggan, Megan; Walker, Christopher J; Markowitz, Joseph; Carson, William E; Eisfeld, Ann-Kathrin; de la Chapelle, Albert.

Proc Natl Acad Sci U S A ; 112(49): E6744-51, 2015 Dec 08.

Artigo em Inglês | MEDLINE | ID: mdl-26582795

14.

ON TRacK towards novel targets in leukemia.

Eisfeld, Ann-Kathrin.

Blood ; 135(24): 2117-2119, 2020 06 11.

Artigo em Inglês | MEDLINE | ID: mdl-32526020

15.

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia.

Papaioannou, Dimitrios; Nicolet, Deedra; Volinia, Stefano; Mrózek, Krzysztof; Yan, Pearlly; Bundschuh, Ralf; Carroll, Andrew J; Kohlschmidt, Jessica; Blum, William; Powell, Bayard L; Uy, Geoffrey L; Kolitz, Jonathan E; Wang, Eunice S; Eisfeld, Ann-Kathrin; Orwick, Shelley J; Lucas, David M; Caligiuri, Michael A; Stone, Richard M; Byrd, John C; Garzon, Ramiro; Bloomfield, Clara D.

Haematologica ; 102(8): 1391-1400, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28473620

16.

NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.

Eisfeld, Ann-Kathrin; Schwind, Sebastian; Hoag, Kevin W; Walker, Christopher J; Liyanarachchi, Sandya; Patel, Ravi; Huang, Xiaomeng; Markowitz, Joseph; Duan, Wenrui; Otterson, Gregory A; Carson, William E; Marcucci, Guido; Bloomfield, Clara D; de la Chapelle, Albert.

Proc Natl Acad Sci U S A ; 111(11): 4179-84, 2014 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-24586049

17.

Expression and prognostic impact of lncRNAs in acute myeloid leukemia.

Garzon, Ramiro; Volinia, Stefano; Papaioannou, Dimitrios; Nicolet, Deedra; Kohlschmidt, Jessica; Yan, Pearlly S; Mrózek, Krzysztof; Bucci, Donna; Carroll, Andrew J; Baer, Maria R; Wetzler, Meir; Carter, Thomas H; Powell, Bayard L; Kolitz, Jonathan E; Moore, Joseph O; Eisfeld, Ann-Kathrin; Blachly, James S; Blum, William; Caligiuri, Michael A; Stone, Richard M; Marcucci, Guido; Croce, Carlo M; Byrd, John C; Bloomfield, Clara D.

Proc Natl Acad Sci U S A ; 111(52): 18679-84, 2014 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-25512507

18.

MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair.

Walker, Christopher J; Miranda, Mario A; O'Hern, Matthew J; Blachly, James S; Moyer, Cassandra L; Ivanovich, Jennifer; Kroll, Karl W; Eisfeld, Ann-Kathrin; Sapp, Caroline E; Mutch, David G; Cohn, David E; Bundschuh, Ralf; Goodfellow, Paul J.

Hum Mutat ; 37(10): 1004-12, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27346418

19.

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia.

Bhatnagar, Bhavana; Eisfeld, Ann-Kathrin; Nicolet, Deedra; Mrózek, Krzysztof; Blachly, James S; Orwick, Shelley; Lucas, David M; Kohlschmidt, Jessica; Blum, William; Kolitz, Jonathan E; Stone, Richard M; Bloomfield, Clara D; Byrd, John C.

Br J Haematol ; 175(2): 226-236, 2016 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-27476855

20.

Type of prior genotoxic insult determines the genomic characteristics of therapy-related myeloid neoplasms.

Ozga, Michael; Blachly, James; Eisfeld, Ann-Kathrin; Grieselhuber, Nicole; Larkin, Karilyn; Walker, Alison; Bhatnagar, Bhavana; Behbehani, Gregory; Long, Meixiao; Haque, Tamanna; Vasu, Sumithira; Zhao, Weiqiang; Jones, Daniel; Byrd, John C; Mims, Alice S; Saygin, Caner.

Am J Hematol ; 96(7): E223-E225, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-33761147

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Disparities in acute myeloid leukemia treatments and outcomes.

DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia.

High-dimensional genomic feature selection with the ordered stereotype logit model.

Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.

Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.

Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.

Controlled variable selection in Weibull mixture cure models for high-dimensional data.

Discovery of clinically relevant fusions in pediatric cancer.

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia.

Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma.

Acute Myeloid Leukemia Genomics: Impact on Care and Remaining Challenges.

Unbiased decision-making for acute myeloid leukemia still needed.

MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies.

ON TRacK towards novel targets in leukemia.

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia.

NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.

Expression and prognostic impact of lncRNAs in acute myeloid leukemia.

MonoSeq Variant Caller Reveals Novel Mononucleotide Run Indel Mutations in Tumors with Defective DNA Mismatch Repair.

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia.

Type of prior genotoxic insult determines the genomic characteristics of therapy-related myeloid neoplasms.