Detalhe da pesquisa
1.
First-Row Transition Metal Complexes Incorporating the 2-(2'-pyridyl)quinoxaline Ligand (pqx), as Potent Inflammatory Mediators: Cytotoxic Properties and Biological Activities against the Platelet-Activating Factor (PAF) and Thrombin.
Molecules
; 28(19)2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37836742
2.
Deficiency of the serine peptidase Kallikrein 6 does not affect the levels and the pathological accumulation of a-synuclein in mouse brain.
J Neurochem
; 157(6): 2024-2038, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32974895
3.
Changes in the cellular fatty acid profile drive the proteasomal degradation of α-synuclein and enhance neuronal survival.
FASEB J
; 34(11): 15123-15145, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931072
4.
Modulation of ß-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson's disease.
Hum Mol Genet
; 27(10): 1696-1710, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29547959
5.
High discriminatory ability of peripheral and CFSF biomarkers in Lewy body diseases.
J Neural Transm (Vienna)
; 127(3): 311-322, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31912280
6.
How is alpha-synuclein cleared from the cell?
J Neurochem
; 150(5): 577-590, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31069800
7.
Plasma alpha-synuclein levels in patients with Parkinson's disease: a systematic review and meta-analysis.
Neurol Sci
; 40(5): 929-938, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30715632
8.
GABA transmission via ATP-dependent K+ channels regulates α-synuclein secretion in mouse striatum.
Brain
; 139(Pt 3): 871-90, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912647
9.
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity.
Hum Mol Genet
; 23(25): 6732-45, 2014 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092884
10.
Decreased levels of alpha-synuclein in cerebrospinal fluid of patients with clinically isolated syndrome and multiple sclerosis.
J Neurochem
; 134(4): 748-55, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25962981
11.
α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes.
Transl Neurodegener
; 13(1): 11, 2024 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38378800
12.
Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays.
Diagnostics (Basel)
; 13(13)2023 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443586
13.
Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.
J Neurosci
; 30(20): 6838-51, 2010 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20484626
14.
Intrastriatal Administration of Exosome-Associated Pathological Alpha-Synuclein Is Not Sufficient by Itself to Cause Pathology Transmission.
Front Neurosci
; 14: 246, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32372894
15.
Elevated Serum α-Synuclein Levels in Huntington's Disease Patients.
Neuroscience
; 431: 34-39, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32045629
16.
Peripheral alpha-synuclein levels in patients with genetic and non-genetic forms of Parkinson's disease.
Parkinsonism Relat Disord
; 73: 35-40, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234683
17.
Inducible over-expression of wild type alpha-synuclein in human neuronal cells leads to caspase-dependent non-apoptotic death.
J Neurochem
; 109(5): 1348-62, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19476547
18.
Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson's Disease.
Front Mol Neurosci
; 12: 237, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31649506
19.
Neuropsychiatric symptoms and α-Synuclein profile of patients with Parkinson's disease dementia, dementia with Lewy bodies and Alzheimer's disease.
J Neurol
; 265(10): 2295-2301, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30083953
20.
Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype.
Autophagy
; 14(1): 98-119, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29198173