Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Systematic molecular evolution enables robust biomolecule discovery.

DeBenedictis, Erika A; Chory, Emma J; Gretton, Dana W; Wang, Brian; Golas, Stefan; Esvelt, Kevin M.

Nat Methods ; 19(1): 55-64, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34969982

2.

Low-N protein engineering with data-efficient deep learning.

Biswas, Surojit; Khimulya, Grigory; Alley, Ethan C; Esvelt, Kevin M; Church, George M.

Nat Methods ; 18(4): 389-396, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33828272

3.

Insidious Insights: Implications of viral vector engineering for pathogen enhancement.

Sandbrink, Jonas B; Alley, Ethan C; Watson, Matthew C; Koblentz, Gregory D; Esvelt, Kevin M.

Gene Ther ; 30(5): 407-410, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-35264741

4.

Enabling high-throughput biology with flexible open-source automation.

Chory, Emma J; Gretton, Dana W; DeBenedictis, Erika A; Esvelt, Kevin M.

Mol Syst Biol ; 17(3): e9942, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33764680

5.

Daisy-chain gene drives for the alteration of local populations.

Noble, Charleston; Min, John; Olejarz, Jason; Buchthal, Joanna; Chavez, Alejandro; Smidler, Andrea L; DeBenedictis, Erika A; Church, George M; Nowak, Martin A; Esvelt, Kevin M.

Proc Natl Acad Sci U S A ; 116(17): 8275-8282, 2019 04 23.

Artigo em Inglês | MEDLINE | ID: mdl-30940750

6.

Inoculating science against potential pandemics and information hazards.

Esvelt, Kevin M.

PLoS Pathog ; 14(10): e1007286, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30286188

7.

Conservation demands safe gene drive.

Esvelt, Kevin M; Gemmell, Neil J.

PLoS Biol ; 15(11): e2003850, 2017 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-29145398

8.

A system for the continuous directed evolution of biomolecules.

Esvelt, Kevin M; Carlson, Jacob C; Liu, David R.

Nature ; 472(7344): 499-503, 2011 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-21478873

9.

Cas9 as a versatile tool for engineering biology.

Mali, Prashant; Esvelt, Kevin M; Church, George M.

Nat Methods ; 10(10): 957-63, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-24076990

10.

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.

Esvelt, Kevin M; Mali, Prashant; Braff, Jonathan L; Moosburner, Mark; Yaung, Stephanie J; Church, George M.

Nat Methods ; 10(11): 1116-21, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24076762

11.

Heritable genome editing in C. elegans via a CRISPR-Cas9 system.

Friedland, Ari E; Tzur, Yonatan B; Esvelt, Kevin M; Colaiácovo, Monica P; Church, George M; Calarco, John A.

Nat Methods ; 10(8): 741-3, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23817069

12.

Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution.

Dickinson, Bryan C; Leconte, Aaron M; Allen, Benjamin; Esvelt, Kevin M; Liu, David R.

Proc Natl Acad Sci U S A ; 110(22): 9007-12, 2013 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-23674678

13.

Genome-scale engineering for systems and synthetic biology.

Esvelt, Kevin M; Wang, Harris H.

Mol Syst Biol ; 9: 641, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23340847

14.

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

Smidler, Andrea L; Marrogi, Eryney; Kauffman, Jamie; Paton, Douglas G; Westervelt, Kathleen A; Church, George M; Esvelt, Kevin M; Shaw, W Robert; Catteruccia, Flaminia.

Sci Rep ; 14(1): 4057, 2024 02 19.

Artigo em Inglês | MEDLINE | ID: mdl-38374393

15.

PyLabRobot: An Open-Source, Hardware Agnostic Interface for Liquid-Handling Robots and Accessories.

Wierenga, Rick P; Golas, Stefan; Ho, Wilson; Coley, Connor; Esvelt, Kevin M.

bioRxiv ; 2023 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-37502883

16.

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

Smidler, Andrea L; Paton, Douglas G; Church, George M; Esvelt, Kevin M; Shaw, W Robert; Catteruccia, Flaminia.

bioRxiv ; 2023 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-37398131

17.

Unnatural Responsibilities.

Esvelt, Kevin M.

Sci Am ; 316(4): 50-51, 2017 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-28296855

18.

Measuring the tolerance of the genetic code to altered codon size.

DeBenedictis, Erika Alden; Söll, Dieter; Esvelt, Kevin M.

Elife ; 112022 03 16.

Artigo em Inglês | MEDLINE | ID: mdl-35293861

19.

Analysis of the first genetic engineering attribution challenge.

Crook, Oliver M; Warmbrod, Kelsey Lane; Lipstein, Greg; Chung, Christine; Bakerlee, Christopher W; McKelvey, T Greg; Holland, Shelly R; Swett, Jacob L; Esvelt, Kevin M; Alley, Ethan C; Bradshaw, William J.

Nat Commun ; 13(1): 7374, 2022 11 30.

Artigo em Inglês | MEDLINE | ID: mdl-36450726

20.

Direct and indirect impacts of synthetic biology on biodiversity conservation.

Macfarlane, Nicholas B W; Adams, Jonathan; Bennett, Elizabeth L; Brooks, Thomas M; Delborne, Jason A; Eggermont, Hilde; Endy, Drew; Esvelt, Kevin M; Kolodziejczyk, Bartlomiej; Kuiken, Todd; Oliva, Maria Julia; Peña Moreno, Sonia; Slobodian, Lydia; Smith, Risa B; Thizy, Delphine; Tompkins, Daniel M; Wei, Wei; Redford, Kent H.

iScience ; 25(11): 105423, 2022 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-36388962

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Systematic molecular evolution enables robust biomolecule discovery.

Low-N protein engineering with data-efficient deep learning.

Insidious Insights: Implications of viral vector engineering for pathogen enhancement.

Enabling high-throughput biology with flexible open-source automation.

Daisy-chain gene drives for the alteration of local populations.

Inoculating science against potential pandemics and information hazards.

Conservation demands safe gene drive.

A system for the continuous directed evolution of biomolecules.

Cas9 as a versatile tool for engineering biology.

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.

Heritable genome editing in C. elegans via a CRISPR-Cas9 system.

Experimental interrogation of the path dependence and stochasticity of protein evolution using phage-assisted continuous evolution.

Genome-scale engineering for systems and synthetic biology.

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

PyLabRobot: An Open-Source, Hardware Agnostic Interface for Liquid-Handling Robots and Accessories.

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

Unnatural Responsibilities.

Measuring the tolerance of the genetic code to altered codon size.

Analysis of the first genetic engineering attribution challenge.

Direct and indirect impacts of synthetic biology on biodiversity conservation.