Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.

Bruno, Ludovica; Ramlall, Vijendra; Studer, Romain A; Sauer, Stephan; Bradley, David; Dharmalingam, Gopuraja; Carroll, Thomas; Ghoneim, Mohamed; Chopin, Michaël; Nutt, Stephen L; Elderkin, Sarah; Rueda, David S; Fisher, Amanda G; Siggers, Trevor; Beltrao, Pedro; Merkenschlager, Matthias.

Nat Immunol ; 20(10): 1372-1380, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31451789

2.

Avrion Mitchison (1928-2022).

Fisher, Amanda G; Merkenschlager, Matthias.

Nat Immunol ; 24(4): 559, 2023 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-36879068

3.

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.

Cuartero, Sergi; Weiss, Felix D; Dharmalingam, Gopuraja; Guo, Ya; Ing-Simmons, Elizabeth; Masella, Silvia; Robles-Rebollo, Irene; Xiao, Xiaolin; Wang, Yi-Fang; Barozzi, Iros; Djeghloul, Dounia; Amano, Mariane T; Niskanen, Henri; Petretto, Enrico; Dowell, Robin D; Tachibana, Kikuë; Kaikkonen, Minna U; Nasmyth, Kim A; Lenhard, Boris; Natoli, Gioacchino; Fisher, Amanda G; Merkenschlager, Matthias.

Nat Immunol ; 19(9): 932-941, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-30127433

4.

Chromatin jets define the properties of cohesin-driven in vivo loop extrusion.

Guo, Ya; Al-Jibury, Ediem; Garcia-Millan, Rosalba; Ntagiantas, Konstantinos; King, James W D; Nash, Alex J; Galjart, Niels; Lenhard, Boris; Rueckert, Daniel; Fisher, Amanda G; Pruessner, Gunnar; Merkenschlager, Matthias.

Mol Cell ; 82(20): 3769-3780.e5, 2022 10 20.

Artigo em Inglês | MEDLINE | ID: mdl-36182691

5.

DNA synthesis is required for reprogramming mediated by stem cell fusion.

Tsubouchi, Tomomi; Soza-Ried, Jorge; Brown, Karen; Piccolo, Francesco M; Cantone, Irene; Landeira, David; Bagci, Hakan; Hochegger, Helfrid; Merkenschlager, Matthias; Fisher, Amanda G.

Cell ; 152(4): 873-83, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23415233

6.

Illuminating Epigenetics and Inheritance in the Immune System with Bioluminescence.

Dimond, Andrew; Van de Pette, Mathew; Fisher, Amanda G.

Trends Immunol ; 41(11): 994-1005, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-33036908

7.

Cohesins functionally associate with CTCF on mammalian chromosome arms.

Parelho, Vania; Hadjur, Suzana; Spivakov, Mikhail; Leleu, Marion; Sauer, Stephan; Gregson, Heather C; Jarmuz, Adam; Canzonetta, Claudia; Webster, Zoe; Nesterova, Tatyana; Cobb, Bradley S; Yokomori, Kyoko; Dillon, Niall; Aragon, Luis; Fisher, Amanda G; Merkenschlager, Matthias.

Cell ; 132(3): 422-33, 2008 Feb 08.

Artigo em Inglês | MEDLINE | ID: mdl-18237772

8.

Initiation and maintenance of pluripotency gene expression in the absence of cohesin.

Lavagnolli, Thais; Gupta, Preksha; Hörmanseder, Eva; Mira-Bontenbal, Hegias; Dharmalingam, Gopuraja; Carroll, Thomas; Gurdon, John B; Fisher, Amanda G; Merkenschlager, Matthias.

Genes Dev ; 29(1): 23-38, 2015 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25561493

9.

Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.

Ferreirós-Vidal, Isabel; Carroll, Thomas; Zhang, Tianyi; Lagani, Vincenzo; Ramirez, Ricardo N; Ing-Simmons, Elizabeth; Gómez-Valadés, Alicia G; Cooper, Lee; Liang, Ziwei; Papoutsoglou, Georgios; Dharmalingam, Gopuraja; Guo, Ya; Tarazona, Sonia; Fernandes, Sunjay J; Noori, Peri; Silberberg, Gilad; Fisher, Amanda G; Tsamardinos, Ioannis; Mortazavi, Ali; Lenhard, Boris; Conesa, Ana; Tegner, Jesper; Merkenschlager, Matthias; Gomez-Cabrero, David.

PLoS Biol ; 17(4): e2006506, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30978178

10.

Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.

Piccolo, Francesco M; Bagci, Hakan; Brown, Karen E; Landeira, David; Soza-Ried, Jorge; Feytout, Amelie; Mooijman, Dylan; Hajkova, Petra; Leitch, Harry G; Tada, Takashi; Kriaucionis, Skirmantas; Dawlaty, Meelad M; Jaenisch, Rudolf; Merkenschlager, Matthias; Fisher, Amanda G.

Mol Cell ; 49(6): 1023-33, 2013 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-23453809

11.

An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.

Fisher, Cynthia L; Marks, Hendrik; Cho, Lily Ting-Yin; Andrews, Robert; Wormald, Sam; Carroll, Thomas; Iyer, Vivek; Tate, Peri; Rosen, Barry; Stunnenberg, Hendrik G; Fisher, Amanda G; Skarnes, William C.

Nucleic Acids Res ; 45(21): e174, 2017 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-28981838

12.

Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin.

Ing-Simmons, Elizabeth; Seitan, Vlad C; Faure, Andre J; Flicek, Paul; Carroll, Thomas; Dekker, Job; Fisher, Amanda G; Lenhard, Boris; Merkenschlager, Matthias.

Genome Res ; 25(4): 504-13, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25677180

13.

Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

Kanhere, Aditi; Viiri, Keijo; Araújo, Carla C; Rasaiyaah, Jane; Bouwman, Russell D; Whyte, Warren A; Pereira, C Filipe; Brookes, Emily; Walker, Kimberly; Bell, George W; Pombo, Ana; Fisher, Amanda G; Young, Richard A; Jenner, Richard G.

Mol Cell ; 38(5): 675-88, 2010 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-20542000

14.

microRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.

Blevins, Rory; Bruno, Ludovica; Carroll, Thomas; Elliott, James; Marcais, Antoine; Loh, Christina; Hertweck, Arnulf; Krek, Azra; Rajewsky, Nikolaus; Chen, Chang-Zheng; Fisher, Amanda G; Merkenschlager, Matthias.

PLoS Genet ; 11(2): e1005020, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-25714103

15.

A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation.

Seitan, Vlad C; Hao, Bingtao; Tachibana-Konwalski, Kikuë; Lavagnolli, Thais; Mira-Bontenbal, Hegias; Brown, Karen E; Teng, Grace; Carroll, Tom; Terry, Anna; Horan, Katie; Marks, Hendrik; Adams, David J; Schatz, David G; Aragon, Luis; Fisher, Amanda G; Krangel, Michael S; Nasmyth, Kim; Merkenschlager, Matthias.

Nature ; 476(7361): 467-71, 2011 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-21832993

16.

Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression.

Savarese, Fabio; Dávila, Amparo; Nechanitzky, Robert; De La Rosa-Velazquez, Inti; Pereira, Carlos F; Engelke, Rudolf; Takahashi, Keiko; Jenuwein, Thomas; Kohwi-Shigematsu, Terumi; Fisher, Amanda G; Grosschedl, Rudolf.

Genes Dev ; 23(22): 2625-38, 2009 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-19933152

17.

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.

Seitan, Vlad C; Faure, Andre J; Zhan, Ye; McCord, Rachel Patton; Lajoie, Bryan R; Ing-Simmons, Elizabeth; Lenhard, Boris; Giorgetti, Luca; Heard, Edith; Fisher, Amanda G; Flicek, Paul; Dekker, Job; Merkenschlager, Matthias.

Genome Res ; 23(12): 2066-77, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24002784

18.

Can controversies be put to REST?

Jørgensen, Helle F; Fisher, Amanda G.

Nature ; 467(7311): E3-4; discussion E5, 2010 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-20811409

19.

Epigenetic memory and parliamentary privilege combine to evoke discussions on inheritance.

Fisher, Amanda G; Brockdorff, Neil.

Development ; 139(21): 3891-6, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23048179

20.

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation.

Ferreirós-Vidal, Isabel; Carroll, Thomas; Taylor, Benjamin; Terry, Anna; Liang, Ziwei; Bruno, Ludovica; Dharmalingam, Gopuraja; Khadayate, Sanjay; Cobb, Bradley S; Smale, Stephen T; Spivakov, Mikhail; Srivastava, Prashant; Petretto, Enrico; Fisher, Amanda G; Merkenschlager, Matthias.

Blood ; 121(10): 1769-82, 2013 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-23303821

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