Detalhe da pesquisa
1.
Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes.
Mol Cell
; 79(5): 812-823.e4, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668201
2.
SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription.
Mol Cell
; 70(4): 679-694.e7, 2018 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29775582
3.
Structural and Functional Impacts of ER Coactivator Sequential Recruitment.
Mol Cell
; 67(5): 733-743.e4, 2017 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28844863
4.
Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.
Nature
; 556(7700): 249-254, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29615789
5.
Structure of a biologically active estrogen receptor-coactivator complex on DNA.
Mol Cell
; 57(6): 1047-1058, 2015 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728767
6.
Histone Marks in the 'Driver's Seat': Functional Roles in Steering the Transcription Cycle.
Trends Biochem Sci
; 42(12): 977-989, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29122461
7.
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics.
Mol Cell
; 51(2): 185-99, 2013 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23850489
8.
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells.
Mol Pharmacol
; 98(1): 24-37, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32362585
9.
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.
J Biol Chem
; 292(35): 14456-14472, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28717009
10.
SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis.
Proc Natl Acad Sci U S A
; 112(44): E6068-77, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26487680
11.
Long Noncoding RNAs as Targets and Regulators of Nuclear Receptors.
Curr Top Microbiol Immunol
; 394: 143-76, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26362934
12.
The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.
Mol Pharmacol
; 89(1): 14-26, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26487511
13.
Disrupting a negative feedback loop drives endocrine therapy-resistant breast cancer.
Proc Natl Acad Sci U S A
; 115(33): 8236-8238, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30082387
14.
RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators.
Proc Natl Acad Sci U S A
; 110(16): 6536-41, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23550157
15.
PKMYT1 is a Marker of Treatment Response and a Therapeutic Target for CDK4/6 Inhibitor-Resistance in ER+ Breast Cancer.
Mol Cancer Ther
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38781103
16.
A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis.
Nat Commun
; 15(1): 1947, 2024 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38431630
17.
Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer.
Cancer Res
; 83(19): 3237-3251, 2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071495
18.
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer.
Mol Cancer Ther
; 20(1): 11-25, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177154
19.
Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer.
Cancer Res
; 81(24): 6259-6272, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34711608
20.
Hormonal modulation of ESR1 mutant metastasis.
Oncogene
; 40(5): 997-1011, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33323970