Detalhe da pesquisa
1.
Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment.
Proc Natl Acad Sci U S A
; 120(29): e2214320120, 2023 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37428918
2.
Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)-b-poly(l-lysine).
Biomacromolecules
; 23(1): 388-397, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34935361
3.
Effective mRNA Protection by Poly(l-ornithine) Synergizes with Endosomal Escape Functionality of a Charge-Conversion Polymer toward Maximizing mRNA Introduction Efficiency.
Macromol Rapid Commun
; 43(12): e2100754, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286740
4.
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier.
Angew Chem Int Ed Engl
; 59(21): 8173-8180, 2020 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31995252
5.
Influence of RNA Strand Rigidity on Polyion Complex Formation with Block Catiomers.
Macromol Rapid Commun
; 37(6): 486-93, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26765970
6.
Systemically Injectable Enzyme-Loaded Polyion Complex Vesicles as In Vivo Nanoreactors Functioning in Tumors.
Angew Chem Int Ed Engl
; 55(2): 560-5, 2016 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26629778
7.
Increased Enzyme Loading in PICsomes via Controlling Membrane Permeability Improves Enzyme Prodrug Cancer Therapy Outcome.
Polymers (Basel)
; 15(6)2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36987149
8.
Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance.
Biomater Sci
; 11(7): 2336-2347, 2023 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36804651
9.
Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models.
Nat Commun
; 13(1): 7165, 2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36418896
10.
Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines.
Biomacromolecules
; 12(9): 3174-85, 2011 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21863796
11.
Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine).
J Control Release
; 330: 812-820, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417983
12.
Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain.
J Control Release
; 332: 260-268, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33647431
13.
Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells.
Biomater Sci
; 9(21): 7076-7091, 2021 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34397074
14.
Effect of Mixing Ratio of Oppositely Charged Block Copolymers on Polyion Complex Micelles for In Vivo Application.
Polymers (Basel)
; 13(1)2020 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375035
15.
Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening.
Adv Healthc Mater
; 9(16): e2000538, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32583633
16.
Structural Control of Boronic Acid Ligands Enhances Intratumoral Targeting of Sialic Acid To Eradicate Cancer Stem-like Cells.
ACS Appl Bio Mater
; 3(8): 5030-5039, 2020 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35021680
17.
Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines.
Sci Adv
; 6(26): eabb8133, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637625
18.
Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain.
ACS Nano
; 14(6): 6729-6742, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32431145
19.
Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability.
J Drug Target
; 27(5-6): 670-680, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30499743
20.
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers.
Nat Commun
; 10(1): 1894, 2019 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31019193