Detalhe da pesquisa
1.
ABCA12 regulates insulin secretion from ß-cells.
EMBO Rep
; 21(3): e48692, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32072744
2.
Deficiency of the innate immune adaptor STING promotes autoreactive T cell expansion in NOD mice.
Diabetologia
; 64(4): 878-889, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33483762
3.
Perforin facilitates beta cell killing and regulates autoreactive CD8+ T-cell responses to antigen in mouse models of type 1 diabetes.
Immunol Cell Biol
; 94(4): 334-41, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446877
4.
Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes.
Diabetologia
; 58(1): 140-8, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25301392
5.
Intra-islet proliferation of cytotoxic T lymphocytes contributes to insulitis progression.
Eur J Immunol
; 42(7): 1717-22, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22585671
6.
Autoreactive cytotoxic T lymphocytes acquire higher expression of cytotoxic effector markers in the islets of NOD mice after priming in pancreatic lymph nodes.
Am J Pathol
; 178(6): 2716-25, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21641394
7.
Diabetes induced by checkpoint inhibition in nonobese diabetic mice can be prevented or reversed by a JAK1/JAK2 inhibitor.
Clin Transl Immunology
; 11(11): e1425, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36325490
8.
Neuropeptide Y1 receptor antagonism protects ß-cells and improves glycemic control in type 2 diabetes.
Mol Metab
; 55: 101413, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890851
9.
The pro-apoptotic BH3-only protein Bid is dispensable for development of insulitis and diabetes in the non-obese diabetic mouse.
Apoptosis
; 16(8): 822-30, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21644000
10.
Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity.
Hepatology
; 52(5): 1632-42, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20799351
11.
IL-17F induces inflammation, dysfunction and cell death in mouse islets.
Sci Rep
; 10(1): 13077, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32753746
12.
The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.
Front Immunol
; 11: 588543, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33343569
13.
Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice.
Cell Death Discov
; 5: 136, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552143
14.
IL-21 regulates SOCS1 expression in autoreactive CD8+ T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice.
Sci Rep
; 9(1): 15302, 2019 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31653894
15.
Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice.
Diabetes
; 66(6): 1650-1660, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28292965
16.
Granzyme A Deficiency Breaks Immune Tolerance and Promotes Autoimmune Diabetes Through a Type I Interferon-Dependent Pathway.
Diabetes
; 66(12): 3041-3050, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28733313
17.
Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets.
PLoS One
; 9(11): e113128, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25405767
18.
Deficiency in type I interferon signaling prevents the early interferon-induced gene signature in pancreatic islets but not type 1 diabetes in NOD mice.
Diabetes
; 63(3): 1032-40, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24353186
19.
The protective effects of CD39 overexpression in multiple low-dose streptozotocin-induced diabetes in mice.
Diabetes
; 62(6): 2026-35, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364452
20.
Complete diabetes protection despite delayed thymic tolerance in NOD8.3 TCR transgenic mice due to antigen-induced extrathymic deletion of T cells.
Diabetes
; 61(2): 425-35, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22190647