Detalhe da pesquisa
1.
Reversible Chemical Modification of Antibody Effector Function Mitigates Unwanted Systemic Immune Activation.
Bioconjug Chem
; 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38789102
2.
Brentuximab Vedotin-Driven Microtubule Disruption Results in Endoplasmic Reticulum Stress Leading to Immunogenic Cell Death and Antitumor Immunity.
Mol Cancer Ther
; 23(1): 68-83, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775098
3.
Neutralization of soluble, synaptotoxic amyloid ß species by antibodies is epitope specific.
J Neurosci
; 32(8): 2696-702, 2012 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22357853
4.
Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity.
Front Immunol
; 14: 1280986, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38022590
5.
SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models.
J Immunother Cancer
; 11(10)2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37793853
6.
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages.
J Cell Biol
; 174(4): 547-56, 2006 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16908670
7.
Therapeutic and Prophylactic Antitumor Activity of an Oral Inhibitor of Fucosylation in Spontaneous Mammary Cancers.
Mol Cancer Ther
; 19(5): 1102-1109, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32165557
8.
Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha.
Am J Respir Crit Care Med
; 178(2): 158-67, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18420961
9.
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions.
Sci Rep
; 9(1): 16947, 2019 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740740
10.
Recognition ligands on apoptotic cells: a perspective.
J Leukoc Biol
; 79(5): 896-903, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16641135
11.
Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth.
Circ Res
; 92(10): 1162-9, 2003 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-12714563
12.
Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms.
PLoS One
; 9(8): e102909, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25170892
13.
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.
PLoS One
; 9(2): e87133, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24551051
14.
Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis.
PLoS One
; 8(6): e66164, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23799078
15.
Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease.
PLoS One
; 8(8): e71634, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24058406
16.
Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS.
PLoS One
; 7(7): e40443, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22792325
17.
TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms.
J Immunol
; 178(12): 8117-26, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548650
18.
Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages.
J Biol Chem
; 281(50): 38376-84, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17056601
19.
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte.
Cell
; 123(2): 321-34, 2005 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16239148
20.
Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP.
J Biol Chem
; 279(43): 44695-703, 2004 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15292176