Detalhe da pesquisa
1.
Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia.
N Engl J Med
; 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38804517
2.
Olezarsen for Hypertriglyceridemia in Patients at High Cardiovascular Risk.
N Engl J Med
; 390(19): 1770-1780, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587249
3.
Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia.
N Engl J Med
; 2024 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38809174
4.
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease.
N Engl J Med
; 387(20): 1855-1864, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36342163
5.
Evolocumab Treatment in Pediatric Patients With Homozygous Familial Hypercholesterolemia: Pooled Data From Three Open-Label Studies.
Arterioscler Thromb Vasc Biol
; 44(5): 1156-1164, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545781
6.
2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance.
Eur Heart J
; 44(25): 2277-2291, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37130090
7.
Evinacumab in Patients with Refractory Hypercholesterolemia.
N Engl J Med
; 383(24): 2307-2319, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33196153
8.
Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia.
N Engl J Med
; 383(14): 1317-1327, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865373
9.
Evinacumab for Homozygous Familial Hypercholesterolemia.
N Engl J Med
; 383(8): 711-720, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32813947
10.
Inhibition of Angiopoietin-Like Protein 3 or 3/8 Complex and ApoC-III in Severe Hypertriglyceridemia.
Curr Atheroscler Rep
; 25(12): 1101-1111, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38095804
11.
Apolipoprotein C-III reduction in subjects with moderate hypertriglyceridaemia and at high cardiovascular risk.
Eur Heart J
; 43(14): 1401-1412, 2022 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35025993
12.
Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.
N Engl J Med
; 381(6): 531-542, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31390500
13.
A variant near DHCR24 associates with microstructural properties of white matter and peripheral lipid metabolism in adolescents.
Mol Psychiatry
; 26(8): 3795-3805, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900429
14.
Genetic burden linked to founder effects in Saguenay-Lac-Saint-Jean illustrates the importance of genetic screening test availability.
J Med Genet
; 58(10): 653-665, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33910931
15.
Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.
Eur Heart J
; 42(47): 4791-4806, 2021 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34472586
16.
Vupanorsen, an N-acetyl galactosamine-conjugated antisense drug to ANGPTL3 mRNA, lowers triglycerides and atherogenic lipoproteins in patients with diabetes, hepatic steatosis, and hypertriglyceridaemia.
Eur Heart J
; 41(40): 3936-3945, 2020 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32860031
17.
Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity.
Arterioscler Thromb Vasc Biol
; 39(11): 2248-2260, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578082
18.
Association of common gene-smoking interactions with elevated plasma apolipoprotein B concentration.
Lipids Health Dis
; 19(1): 98, 2020 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32430061
19.
The burden of familial chylomicronemia syndrome in Canadian patients.
Lipids Health Dis
; 19(1): 120, 2020 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32487261
20.
Omega-3 fatty acid exposure with a low-fat diet in patients with past hypertriglyceridemia-induced acute pancreatitis; an exploratory, randomized, open-label crossover study.
Lipids Health Dis
; 19(1): 117, 2020 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32473640