Detalhe da pesquisa
1.
Hepatic NADH reductive stress underlies common variation in metabolic traits.
Nature
; 583(7814): 122-126, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461692
2.
Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome.
Mol Genet Metab
; 133(1): 83-93, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33752971
3.
Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter.
Proc Natl Acad Sci U S A
; 114(43): E9096-E9104, 2017 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29073106
4.
Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.
Proc Natl Acad Sci U S A
; 114(21): E4241-E4250, 2017 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28483998
5.
Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome.
Am J Physiol Lung Cell Mol Physiol
; 316(2): L391-L399, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520688
6.
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
Nature
; 476(7360): 341-5, 2011 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21685886
7.
Systematic identification of human mitochondrial disease genes through integrative genomics.
Nat Genet
; 38(5): 576-82, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16582907
8.
ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.
Cell Metab
; 36(1): 144-158.e7, 2024 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38101397
9.
A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells.
Proc Natl Acad Sci U S A
; 107(4): 1571-5, 2010 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20080599
10.
Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS.
Nat Commun
; 13(1): 2483, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35513392
11.
Evolutionary divergence reveals the molecular basis of EMRE dependence of the human MCU.
Life Sci Alliance
; 3(10)2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32769116
12.
Exploring the In Vivo Role of the Mitochondrial Calcium Uniporter in Brown Fat Bioenergetics.
Cell Rep
; 27(5): 1364-1375.e5, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31042465
13.
Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation.
Cell Metab
; 30(4): 824-832.e3, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31402314
14.
Hypoxia as a therapy for mitochondrial disease.
Science
; 352(6281): 54-61, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917594
15.
Mitochondrial dysfunction remodels one-carbon metabolism in human cells.
Elife
; 52016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27307216
16.
EMRE is an essential component of the mitochondrial calcium uniporter complex.
Science
; 342(6164): 1379-82, 2013 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24231807
17.
Mutations in MTFMT underlie a human disorder of formylation causing impaired mitochondrial translation.
Cell Metab
; 14(3): 428-34, 2011 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21907147
18.
High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency.
Nat Genet
; 42(10): 851-8, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818383
19.
Syndecan-1 expression in epithelial cells is induced by transforming growth factor beta through a PKA-dependent pathway.
J Biol Chem
; 281(34): 24365-74, 2006 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16807246
20.
Insulin promotes shedding of syndecan ectodomains from 3T3-L1 adipocytes: a proposed mechanism for stabilization of extracellular lipoprotein lipase.
Biochemistry
; 45(18): 5703-11, 2006 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16669614