Detalhe da pesquisa
1.
Efficacy and safety results of depatuxizumab mafodotin (ABT-414) in patients with advanced solid tumors likely to overexpress epidermal growth factor receptor.
Cancer
; 124(10): 2174-2183, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29533458
2.
Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study.
Lancet Oncol
; 18(11): 1523-1531, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29055736
3.
Epidermal Growth Factor Receptor Inhibition in the Management of Squamous Cell Carcinoma of the Lung.
Oncologist
; 21(2): 205-13, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26768483
4.
Probability of cancer in pulmonary nodules detected on first screening CT.
N Engl J Med
; 369(10): 910-9, 2013 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24004118
5.
A phase I study of high-dose rosuvastatin with standard dose erlotinib in patients with advanced solid malignancies.
J Transl Med
; 14: 83, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27036206
6.
Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung (LUX-Lung 8): an open-label randomised controlled phase 3 trial.
Lancet Oncol
; 16(8): 897-907, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26156651
7.
Epidermal growth factor receptor tyrosine kinase inhibitors in early-stage nonsmall cell lung cancer.
Curr Opin Oncol
; 27(2): 102-7, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25611026
8.
Dacomitinib compared with placebo in pretreated patients with advanced or metastatic non-small-cell lung cancer (NCIC CTG BR.26): a double-blind, randomised, phase 3 trial.
Lancet Oncol
; 15(12): 1379-88, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25439692
9.
Feasibility of real time next generation sequencing of cancer genes linked to drug response: results from a clinical trial.
Int J Cancer
; 132(7): 1547-55, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22948899
10.
Histologic and Genotypic Characterization of Lung Cancer in the Inuit Population of the Eastern Canadian Arctic.
Curr Oncol
; 29(5): 3171-3186, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35621648
11.
CCTG BR34: A Randomized Phase 2 Trial of Durvalumab and Tremelimumab With or Without Platinum-Based Chemotherapy in Patients With Metastatic NSCLC.
J Thorac Oncol
; 17(3): 434-445, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34800700
12.
Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung: Final analysis of the randomised phase 3 LUX-Lung 8 trial.
EClinicalMedicine
; 37: 100940, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34195574
13.
Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer.
Cancer Med
; 10(9): 3045-3058, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33811746
14.
A phase IB study of durvalumab with or without tremelimumab and platinum-doublet chemotherapy in advanced solid tumours: Canadian Cancer Trials Group Study IND226.
Lung Cancer
; 143: 1-11, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32169783
15.
Improving access to lung cancer treatment in northern Canada: the role of oral molecularly targeted agents.
CMAJ
; 186(7): 485-6, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24566641
16.
Third-generation epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of non-small cell lung cancer.
Transl Lung Cancer Res
; 8(Suppl 3): S247-S264, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31857949
17.
Symptom and Quality of Life Improvement in LUX-Lung 8, an Open-Label Phase III Study of Second-Line Afatinib Versus Erlotinib in Patients With Advanced Squamous Cell Carcinoma of the Lung After First-Line Platinum-Based Chemotherapy.
Clin Lung Cancer
; 19(1): 74-83.e11, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28729180
18.
Update on International Cooperative Groups Studies in Thoracic Malignancies: The Emergence of Immunotherapy.
Clin Lung Cancer
; 19(5): 377-386, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29653819
19.
Association of ERBB Mutations With Clinical Outcomes of Afatinib- or Erlotinib-Treated Patients With Lung Squamous Cell Carcinoma: Secondary Analysis of the LUX-Lung 8 Randomized Clinical Trial.
JAMA Oncol
; 4(9): 1189-1197, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29902295
20.
Plasma ctDNA Analysis for Detection of the EGFR T790M Mutation in Patients with Advanced Non-Small Cell Lung Cancer.
J Thorac Oncol
; 12(7): 1061-1070, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28428148