Detalhe da pesquisa
1.
An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35210363
2.
Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL.
J Lipid Res
; 64(11): 100457, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37832604
3.
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes.
J Am Chem Soc
; 144(14): 6237-6250, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35362954
4.
Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice.
J Lipid Res
; 61(7): 995-1003, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350080
5.
Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL).
Bioorg Med Chem
; 28(16): 115610, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690265
6.
Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption.
J Lipid Res
; 60(7): 1284-1292, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048404
7.
Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans.
J Lipid Res
; 60(5): 1020-1031, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30894461
8.
Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase.
J Lipid Res
; 59(3): 531-541, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326160
9.
Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced Neuroinflammation.
J Biol Chem
; 291(2): 913-23, 2016 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565024
10.
α/ß Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
J Biol Chem
; 290(50): 29869-81, 2015 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491015
11.
Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.
Biochim Biophys Acta
; 1851(7): 937-45, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25732851
12.
Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.
J Hepatol
; 63(2): 437-45, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733154
13.
Development of small-molecule inhibitors targeting adipose triglyceride lipase.
Nat Chem Biol
; 9(12): 785-7, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24096302
14.
Mutational scanning pinpoints distinct binding sites of key ATGL regulators in lipolysis.
Nat Commun
; 15(1): 2516, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38514628
15.
Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.
J Lipid Res
; 54(4): 1092-102, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23345410
16.
Off-target effects of the lysosomal acid lipase inhibitors Lalistat-1 and Lalistat-2 on neutral lipid hydrolases.
Mol Metab
; 61: 101510, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504532
17.
Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: A randomized cross-over trial.
EBioMedicine
; 86: 104349, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36371986
18.
Pharmacological inhibition of adipose tissue adipose triglyceride lipase by Atglistatin prevents catecholamine-induced myocardial damage.
Cardiovasc Res
; 118(11): 2488-2505, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061169
19.
Lipolysis: cellular mechanisms for lipid mobilization from fat stores.
Nat Metab
; 3(11): 1445-1465, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34799702
20.
Astroglial monoacylglycerol lipase controls mutant huntingtin-induced damage of striatal neurons.
Neuropharmacology
; 150: 134-144, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30914306