Detalhe da pesquisa
1.
Early Appearance of Dendritic Alterations in Neocortical Pyramidal Neurons of the Ts65Dn Model of Down Syndrome.
Dev Neurosci
; 44(1): 23-38, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34852343
2.
Treatment with the flavonoid 7,8-Dihydroxyflavone: a promising strategy for a constellation of body and brain disorders.
Crit Rev Food Sci Nutr
; 62(1): 13-50, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-32914634
3.
Obstructive sleep apneas naturally occur in mice during REM sleep and are highly prevalent in a mouse model of Down syndrome.
Neurobiol Dis
; 159: 105508, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509609
4.
Early appearance of developmental alterations in the dendritic tree of the hippocampal granule cells in the Ts65Dn model of Down syndrome.
Hippocampus
; 31(4): 435-447, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33464704
5.
Neonatal therapy with clenbuterol and salmeterol restores spinogenesis and dendritic complexity in the dentate gyrus of the Ts65Dn model of Down syndrome.
Neurobiol Dis
; 140: 104874, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325119
6.
Neonatal treatment with cyclosporine A restores neurogenesis and spinogenesis in the Ts65Dn model of Down syndrome.
Neurobiol Dis
; 129: 44-55, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085229
7.
Neuroanatomical alterations and synaptic plasticity impairment in the perirhinal cortex of the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis
; 106: 89-100, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28651891
8.
Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis
; 103: 11-23, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28359846
9.
Withdrawal: Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation.
J Biol Chem
; 295(10): 3391, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144154
10.
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome.
Neurobiol Dis
; 82: 385-396, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26254735
11.
Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice.
Neurobiol Dis
; 74: 204-18, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25497735
12.
Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model.
Brain
; 137(Pt 2): 380-401, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24334313
13.
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Hum Mol Genet
; 20(8): 1560-73, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266456
14.
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression.
Lab Invest
; 92(11): 1648-60, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22890555
15.
Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome.
J Neurosci
; 30(26): 8769-79, 2010 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20592198
16.
Is it possible to improve neurodevelopmental abnormalities in Down syndrome?
Rev Neurosci
; 22(4): 419-55, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21819263
17.
Impaired Brain Mitochondrial Bioenergetics in the Ts65Dn Mouse Model of Down Syndrome Is Restored by Neonatal Treatment with the Polyphenol 7,8-Dihydroxyflavone.
Antioxidants (Basel)
; 11(1)2021 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052567
18.
The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome.
Sci Rep
; 11(1): 6300, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737521
19.
Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome.
Clin Neurol Neurosurg
; 194: 105870, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32480293
20.
Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood.
Hippocampus
; 19(8): 763-72, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19156848