Detalhe da pesquisa
1.
Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells.
Proc Natl Acad Sci U S A
; 113(39): E5757-64, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27516545
2.
Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.
Br J Cancer
; 115(6): 682-90, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27529512
3.
The location and development of Replicon Cluster Domains in early replicating DNA.
Wellcome Open Res
; 8: 158, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37766844
4.
Co-localisation of intra-nuclear membrane type-1 matrix metalloproteinase and hypoxia inducible factor-2α in osteosarcoma and prostate carcinoma cells.
Oncol Lett
; 21(2): 158, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33552276
5.
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines.
Cell Chem Biol
; 24(8): 981-992.e4, 2017 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28781123
6.
Pre-clinical use of isogenic cell lines and tumours in vitro and in vivo for predictive biomarker discovery; impact of KRAS and PI3KCA mutation status on MEK inhibitor activity is model dependent.
Eur J Cancer
; 56: 69-76, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26820797
7.
Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037.
Cancer Chemother Pharmacol
; 78(6): 1269-1281, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27837257
8.
Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing.
Nat Cell Biol
; 18(7): 777-89, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27323328
9.
The enhanced in vivo activity of the combination of a MEK and a PI3K inhibitor correlates with [18F]-FLT PET in human colorectal cancer xenograft tumour-bearing mice.
PLoS One
; 8(12): e81763, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24339963