Detalhe da pesquisa
1.
Histopathology is required to identify and characterize myopathies in high-throughput phenotype screening of genetically engineered mice.
Vet Pathol
; 58(6): 1158-1171, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34269122
2.
Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice.
Vet Pathol
; 57(5): 723-735, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32638637
3.
Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library.
Proc Natl Acad Sci U S A
; 114(7): 1708-1713, 2017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28130548
4.
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies.
J Med Chem
; 67(4): 2321-2336, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300987
5.
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex.
J Physiol
; 589(Pt 20): 4857-84, 2011 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21807615
6.
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes.
Diabetes Metab Syndr Obes
; 14: 3753-3785, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34483672
7.
Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers.
Cancer Res
; 81(7): 1627-1632, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33509943
8.
Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity.
Diabetes Metab Syndr Obes
; 13: 2641-2652, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32801815
9.
NOTUM inhibition increases endocortical bone formation and bone strength.
Bone Res
; 7: 2, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622831
10.
PTH stimulates bone formation in mice deficient in Lrp5.
J Bone Miner Res
; 22(3): 394-402, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17147489
11.
Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
Diabetes Metab Syndr Obes
; 9: 185-99, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27382320
12.
Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice.
Front Endocrinol (Lausanne)
; 6: 86, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26082754
13.
Severe retinal degeneration associated with disruption of semaphorin 4A.
Invest Ophthalmol Vis Sci
; 45(8): 2767-77, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15277503
14.
High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.
Bone Res
; 2: 14034, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-26273529
15.
Keratinocyte migration in the developing eyelid requires LIMK2.
PLoS One
; 7(10): e47168, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23071748
16.
Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function.
Mol Cell Biol
; 31(1): 63-80, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20974805
17.
A mouse knockout library for secreted and transmembrane proteins.
Nat Biotechnol
; 28(7): 749-55, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20562862
18.
Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions.
PLoS One
; 4(1): e4112, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19119317
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Genome Res
; 18(10): 1670-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18799693
20.
High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.
Obesity (Silver Spring)
; 16(10): 2362-7, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18719666