Detalhe da pesquisa
1.
Optimization of intestinal microsomal preparation in the rat: A systematic approach to assess the influence of various methodologies on metabolic activity and scaling factors.
Biopharm Drug Dispos
; 38(3): 187-208, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207929
2.
Quantitative ADME proteomics - CYP and UGT enzymes in the Beagle dog liver and intestine.
Pharm Res
; 32(1): 74-90, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25033762
3.
The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.
Pharm Res
; 31(3): 720-30, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072264
4.
Quantifying gut wall metabolism: methodology matters.
Biopharm Drug Dispos
; 38(2): 155-160, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28039878
5.
Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models.
Clin Pharmacokinet
; 55(6): 673-96, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26895020
6.
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination.
AAPS J
; 18(3): 589-604, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26964996
7.
Animal versus human oral drug bioavailability: do they correlate?
Eur J Pharm Sci
; 57: 280-91, 2014 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23988844