Detalhe da pesquisa
1.
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.
EMBO Rep
; 22(12): e52764, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661369
2.
Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.
Nucleic Acids Res
; 49(7): 3856-3875, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33751115
3.
The T850D Phosphomimetic Mutation in the Androgen Receptor Ligand Binding Domain Enhances Recruitment at Activation Function 2.
Int J Mol Sci
; 23(3)2022 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163481
4.
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents.
Bioorg Med Chem Lett
; 28(21): 3472-3476, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30286952
5.
Comparing the rules of engagement of androgen and glucocorticoid receptors.
Cell Mol Life Sci
; 74(12): 2217-2228, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28168446
6.
A satellite cell-specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle.
FASEB J
; 28(7): 2979-94, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24671706
7.
A kindred with mutant IKAROS and autoimmunity.
J Allergy Clin Immunol
; 142(2): 699-702.e12, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29705243
8.
Discovery of a novel androgen receptor antagonist, MEL-6, with stereoselective activity and optimization of its metabolic stability.
J Steroid Biochem Mol Biol
; 239: 106476, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38311010
9.
Structural mechanism underlying variations in DNA binding by the androgen receptor.
J Steroid Biochem Mol Biol
; 241: 106499, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38604378
10.
Rational evolution for altering the ligand preference of estrogen receptor alpha.
Protein Sci
; 33(4): e4940, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38511482
11.
A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene.
FASEB J
; 26(10): 4360-72, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22798427
12.
The genomic landscape of prostate cancer.
Int J Mol Sci
; 14(6): 10822-51, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23708091
13.
Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer.
Protein Sci
; 32(4): e4599, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36806291
14.
Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors.
Mol Cancer Ther
; 21(12): 1823-1834, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36218067
15.
Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay.
J Steroid Biochem Mol Biol
; 217: 106043, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902544
16.
N/C Interactions Are Dispensable for Normal In Vivo Functioning of the Androgen Receptor in Male Mice.
Endocrinology
; 163(9)2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35908178
17.
A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer.
J Cachexia Sarcopenia Muscle
; 13(4): 2242-2253, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35686338
18.
Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer.
Mol Cancer Res
; 20(4): 527-541, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082164
19.
A 629RKLKK633 motif in the hinge region controls the androgen receptor at multiple levels.
Cell Mol Life Sci
; 67(11): 1919-27, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20186458
20.
Structure and stability of the designer protein WRAP-T and its permutants.
Sci Rep
; 11(1): 18867, 2021 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34552189