Detalhe da pesquisa
1.
Crystal Structures of Protein-Bound Cyclic Peptides.
Chem Rev
; 119(17): 9861-9914, 2019 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31046237
2.
Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability.
Angew Chem Int Ed Engl
; 60(15): 8385-8390, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33185961
3.
Structure-Activity Relationships of Wollamide Cyclic Hexapeptides with Activity against Drug-Resistant and Intracellular Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 63(3)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602509
4.
A Novel Long-Range n to π* Interaction Secures the Smallest known α-Helix in Water.
Angew Chem Int Ed Engl
; 58(52): 18873-18877, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31625253
5.
Contiguous hydrophobic and charged surface patches in short helix-constrained peptides drive cell permeability.
Org Biomol Chem
; 16(3): 367-371, 2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29264603
6.
Helix Nucleation by the Smallest Known α-Helix in Water.
Angew Chem Int Ed Engl
; 55(29): 8275-9, 2016 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226426
7.
Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides.
Chembiochem
; 16(16): 2289-93, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26336864
8.
Constraining cyclic peptides to mimic protein structure motifs.
Angew Chem Int Ed Engl
; 53(48): 13020-41, 2014 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25287434
9.
Improving on nature: making a cyclic heptapeptide orally bioavailable.
Angew Chem Int Ed Engl
; 53(45): 12059-63, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25219505
10.
Comparative α-helicity of cyclic pentapeptides in water.
Angew Chem Int Ed Engl
; 53(27): 6965-9, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24828311
11.
Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm.
Dev Cell
; 59(6): 705-722.e8, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38354738
12.
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency.
Proc Natl Acad Sci U S A
; 107(26): 11686-91, 2010 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20543141
13.
Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells.
J Cell Commun Signal
; 17(4): 1293-1307, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37991681
14.
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages.
J Innate Immun
; 15(1): 468-484, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36882040
15.
Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis.
Microbiol Spectr
; 11(4): e0046523, 2023 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37289062
16.
Helical structure in cyclic peptides: effect of N-methyl amides versus esters.
Chem Commun (Camb)
; 58(89): 12475-12478, 2022 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36274265
17.
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles.
J Med Chem
; 65(17): 11759-11775, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35984914
18.
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv
; 7(49): eabg4007, 2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34851660
19.
The antiplasmodial activity of norcantharidin analogs.
Bioorg Med Chem Lett
; 20(22): 6688-95, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20888768
20.
Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities.
Chem Commun (Camb)
; 55(89): 13362-13365, 2019 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31631195