Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

DNA synthesis is required for reprogramming mediated by stem cell fusion.

Tsubouchi, Tomomi; Soza-Ried, Jorge; Brown, Karen; Piccolo, Francesco M; Cantone, Irene; Landeira, David; Bagci, Hakan; Hochegger, Helfrid; Merkenschlager, Matthias; Fisher, Amanda G.

Cell ; 152(4): 873-83, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23415233

2.

Genetic instability from a single S phase after whole-genome duplication.

Gemble, Simon; Wardenaar, René; Keuper, Kristina; Srivastava, Nishit; Nano, Maddalena; Macé, Anne-Sophie; Tijhuis, Andréa E; Bernhard, Sara Vanessa; Spierings, Diana C J; Simon, Anthony; Goundiam, Oumou; Hochegger, Helfrid; Piel, Matthieu; Foijer, Floris; Storchová, Zuzana; Basto, Renata.

Nature ; 604(7904): 146-151, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35355016

3.

DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation.

Lemmens, Bennie; Hegarat, Nadia; Akopyan, Karen; Sala-Gaston, Joan; Bartek, Jiri; Hochegger, Helfrid; Lindqvist, Arne.

Mol Cell ; 71(1): 117-128.e3, 2018 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-30008317

4.

Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B.

Hégarat, Nadia; Crncec, Adrijana; Suarez Peredo Rodriguez, Maria F; Echegaray Iturra, Fabio; Gu, Yan; Busby, Oliver; Lang, Paul F; Barr, Alexis R; Bakal, Chris; Kanemaki, Masato T; Lamond, Angus I; Novak, Bela; Ly, Tony; Hochegger, Helfrid.

EMBO J ; 39(11): e104419, 2020 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-32350921

5.

Author Correction: Genetic instability from a single S phase after whole-genome duplication.

Gemble, Simon; Wardenaar, René; Keuper, Kristina; Srivastava, Nishit; Nano, Maddalena; Macé, Anne-Sophie; Tijhuis, Andréa E; Bernhard, Sara Vanessa; Spierings, Diana C J; Simon, Anthony; Goundiam, Oumou; Hochegger, Helfrid; Piel, Matthieu; Foijer, Floris; Storchová, Zuzana; Basto, Renata.

Nature ; 608(7923): E27, 2022 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-35864235

6.

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

Hochegger, Helfrid; Takeda, Shunichi; Hunt, Tim.

Nat Rev Mol Cell Biol ; 9(11): 910-6, 2008 11.

Artigo em Inglês | MEDLINE | ID: mdl-18813291

7.

Proteomics of a fuzzy organelle: interphase chromatin.

Kustatscher, Georg; Hégarat, Nadia; Wills, Karen L H; Furlan, Cristina; Bukowski-Wills, Jimi-Carlo; Hochegger, Helfrid; Rappsilber, Juri.

EMBO J ; 33(6): 648-64, 2014 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-24534090

8.

Bistability of mitotic entry and exit switches during open mitosis in mammalian cells.

Hégarat, Nadia; Rata, Scott; Hochegger, Helfrid.

Bioessays ; 38(7): 627-43, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27231150

9.

PP2A/B55 and Fcp1 regulate Greatwall and Ensa dephosphorylation during mitotic exit.

Hégarat, Nadia; Vesely, Clare; Vinod, P K; Ocasio, Cory; Peter, Nisha; Gannon, Julian; Oliver, Antony W; Novák, Béla; Hochegger, Helfrid.

PLoS Genet ; 10(1): e1004004, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24391510

10.

Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.

Smith, Ewan; Hégarat, Nadia; Vesely, Clare; Roseboom, Isaac; Larch, Chris; Streicher, Hansjörg; Straatman, Kornelis; Flynn, Helen; Skehel, Mark; Hirota, Toru; Kuriyama, Ryoko; Hochegger, Helfrid.

EMBO J ; 30(11): 2233-45, 2011 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-21522128

11.

An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells.

Hochegger, Helfrid; Dejsuphong, Donniphat; Sonoda, Eiichiro; Saberi, Alihossein; Rajendra, Eeson; Kirk, Jane; Hunt, Tim; Takeda, Shunichi.

J Cell Biol ; 178(2): 257-68, 2007 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-17635936

12.

Degron Tagging Using mAID and SMASh Tags in RPE-1 Cells.

Crncec, Adrijana; Hochegger, Helfrid.

Methods Mol Biol ; 2415: 183-197, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34972955

13.

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase.

Fisher, Anna E O; Hochegger, Helfrid; Takeda, Shunichi; Caldecott, Keith W.

Mol Cell Biol ; 27(15): 5597-605, 2007 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-17548475

14.

RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.

Saberi, Alihossein; Hochegger, Helfrid; Szuts, David; Lan, Li; Yasui, Akira; Sale, Julian E; Taniguchi, Yoshihito; Murakawa, Yasuhiro; Zeng, Weihua; Yokomori, Kyoko; Helleday, Thomas; Teraoka, Hirobumi; Arakawa, Hiroshi; Buerstedde, Jean-Marie; Takeda, Shunichi.

Mol Cell Biol ; 27(7): 2562-71, 2007 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-17242200

15.

Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation.

Stiff, Tom; Echegaray-Iturra, Fabio R; Pink, Harry J; Herbert, Alex; Reyes-Aldasoro, Constantino Carlos; Hochegger, Helfrid.

Cell Rep ; 31(8): 107681, 2020 05 26.

Artigo em Inglês | MEDLINE | ID: mdl-32460023

16.

Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells.

Murakawa, Yasuhiro; Sonoda, Eiichiro; Barber, Louise J; Zeng, Weihua; Yokomori, Kyoko; Kimura, Hiroshi; Niimi, Atsuko; Lehmann, Alan; Zhao, Guang Yu; Hochegger, Helfrid; Boulton, Simon J; Takeda, Shunichi.

Cancer Res ; 67(18): 8536-43, 2007 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-17875693

17.

Triggering mitosis.

Crncec, Adrijana; Hochegger, Helfrid.

FEBS Lett ; 593(20): 2868-2888, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31602636

18.

A Ploidy Increase Promotes Sensitivity of Glioma Stem Cells to Aurora Kinases Inhibition.

Cilibrasi, Chiara; Guzzi, Andrèe; Bazzoni, Riccardo; Riva, Gabriele; Cadamuro, Massimiliano; Hochegger, Helfrid; Bentivegna, Angela.

J Oncol ; 2019: 9014045, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31531022

19.

Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis.

Eykelenboom, John K; Gierlinski, Marek; Yue, Zuojun; Hegarat, Nadia; Pollard, Hilary; Fukagawa, Tatsuo; Hochegger, Helfrid; Tanaka, Tomoyuki U.

J Cell Biol ; 218(5): 1531-1552, 2019 05 06.

Artigo em Inglês | MEDLINE | ID: mdl-30858191

20.

Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis.

Booth, Alexander Jr; Yue, Zuojun; Eykelenboom, John K; Stiff, Tom; Luxton, Gw Gant; Hochegger, Helfrid; Tanaka, Tomoyuki U.

Elife ; 82019 07 03.

Artigo em Inglês | MEDLINE | ID: mdl-31264963

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