Detalhe da pesquisa
1.
Embryo model completes gastrulation to neurulation and organogenesis.
Nature
; 610(7930): 143-153, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36007540
2.
Spatial profiling of early primate gastrulation in utero.
Nature
; 609(7925): 136-143, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35709828
3.
Microgel culture and spatial identity mapping elucidate the signalling requirements for primate epiblast and amnion formation.
Development
; 149(20)2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36125063
4.
Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments.
Chem Rev
; 123(9): 5571-5611, 2023 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37126602
5.
Functional metagenomic screening identifies an unexpected ß-glucuronidase.
Nat Chem Biol
; 18(10): 1096-1103, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799064
6.
Improved RAD51 binders through motif shuffling based on the modularity of BRC repeats.
Proc Natl Acad Sci U S A
; 118(46)2021 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34772801
7.
Ultrahigh-Throughput Directed Evolution of a Metal-Free α/ß-Hydrolase with a Cys-His-Asp Triad into an Efficient Phosphotriesterase.
J Am Chem Soc
; 145(2): 1083-1096, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36583539
8.
Chemoenzymatic Photoreforming: A Sustainable Approach for Solar Fuel Generation from Plastic Feedstocks.
J Am Chem Soc
; 145(37): 20355-20364, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37671930
9.
Ultra-High-Throughput Absorbance-Activated Droplet Sorting for Enzyme Screening at Kilohertz Frequencies.
Anal Chem
; 95(10): 4597-4604, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848587
10.
Global fitness landscapes of the Shine-Dalgarno sequence.
Genome Res
; 30(5): 711-723, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424071
11.
The biosynthesis, degradation, and function of cell wall ß-xylosylated xyloglucan mirrors that of arabinoxyloglucan.
New Phytol
; 240(6): 2353-2371, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37823344
12.
In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region.
Proc Natl Acad Sci U S A
; 117(44): 27307-27318, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067389
13.
High-Throughput Steady-State Enzyme Kinetics Measured in a Parallel Droplet Generation and Absorbance Detection Platform.
Anal Chem
; 94(48): 16701-16710, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417687
14.
Split & mix assembly of DNA libraries for ultrahigh throughput on-bead screening of functional proteins.
Nucleic Acids Res
; 48(11): e63, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32383757
15.
Ultrahigh-throughput screening in microfluidic droplets: a faster route to new enzymes.
Trends Biochem Sci
; 47(5): 451-452, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34848125
16.
Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays.
Anal Chem
; 93(4): 2166-2173, 2021 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397084
17.
Ultrahigh-Throughput Detection of Enzymatic Alcohol Dehydrogenase Activity in Microfluidic Droplets with a Direct Fluorogenic Assay.
Chembiochem
; 22(23): 3292-3299, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34643305
18.
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc Natl Acad Sci U S A
; 115(31): E7293-E7302, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012610
19.
"NAD-display": Ultrahigh-Throughput in Vitro Screening of NAD(H) Dehydrogenases Using Bead Display and Flow Cytometry.
Angew Chem Int Ed Engl
; 60(16): 9015-9021, 2021 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33470025
20.
Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
Angew Chem Int Ed Engl
; 60(19): 10919-10927, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33616271