Detalhe da pesquisa
1.
Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy.
Nature
; 489(7414): 155-9, 2012 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22820254
2.
Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms.
Proc Natl Acad Sci U S A
; 111(50): E5401-10, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25516983
3.
Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis.
Blood
; 123(22): e123-33, 2014 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24740812
4.
Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome.
Blood
; 119(19): 4480-5, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22431577
5.
Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera.
Am J Hematol
; 88(9): 723-9, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23720412
6.
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Nat Med
; 22(7): 792-9, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27322744
7.
The polycomb group protein L3MBTL1 represses a SMAD5-mediated hematopoietic transcriptional program in human pluripotent stem cells.
Stem Cell Reports
; 4(4): 658-69, 2015 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25754204
8.
Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Elife
; 42015 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26575292
9.
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia.
Cancer Cell
; 27(4): 502-15, 2015 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25873173
10.
JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.
Cancer Discov
; 5(3): 316-31, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25572172
11.
Loss of BAP1 function leads to EZH2-dependent transformation.
Nat Med
; 21(11): 1344-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437366
12.
Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation.
J Leuk (Los Angel)
; 2(3)2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28239612
13.
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Cell Rep
; 9(5): 1841-1855, 2014 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25482556
14.
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.
J Exp Med
; 210(12): 2641-59, 2013 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24218140
15.
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.
Cancer Cell
; 22(2): 180-93, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22897849
16.
Chromatin structure predicts epigenetic therapy responsiveness in sarcoma.
Mol Cancer Ther
; 10(2): 313-24, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21216937
17.
Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.
Clin Transl Oncol
; 13(3): 194-203, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21421465
18.
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".
Nat Med
; 22(6): 578-9, 2016 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27270773
19.
MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century.
Expert Rev Anticancer Ther
; 9(8): 1135-44, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19671033
20.
Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivo.
Hum Cell
; 22(4): 85-93, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19874397