Detalhe da pesquisa
1.
Assigning functionality to cysteines by base editing of cancer dependency genes.
Nat Chem Biol
; 19(11): 1320-1330, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783940
2.
Continuous directed evolution of proteins with improved soluble expression.
Nat Chem Biol
; 14(10): 972-980, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30127387
3.
Repurposing Hsp90 inhibitors as antibiotics targeting histidine kinases.
Bioorg Med Chem Lett
; 27(23): 5235-5244, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110989
4.
High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs.
Nat Biotechnol
; 41(1): 96-107, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36076084
5.
Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity.
Nat Biotechnol
; 41(5): 673-685, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36357719
6.
CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA.
Nat Biotechnol
; 40(9): 1378-1387, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35379961
7.
Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors.
Nat Biomed Eng
; 6(11): 1272-1283, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902773
8.
Precision genome editing using cytosine and adenine base editors in mammalian cells.
Nat Protoc
; 16(2): 1089-1128, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462442
9.
Continuous evolution of SpCas9 variants compatible with non-G PAMs.
Nat Biotechnol
; 38(4): 471-481, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32042170
10.
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells.
Nat Biomed Eng
; 4(1): 111-124, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31937939
11.
Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.
Nat Biotechnol
; 37(7): 820, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182863
12.
Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.
Nat Biotechnol
; 37(6): 626-631, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31110355
13.
Publisher Correction: Efficient in vivo base editing via single adenoassociated viruses with size-optimized genomes encoding compact adenine base editors.
Nat Biomed Eng
; 6(11): 1317, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35931809
14.
Publisher Correction: Precision genome editing using cytosine and adenine base editors in mammalian cells.
Nat Protoc
; 16(12): 5740, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34789924