Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Non-cell-autonomous cancer progression from chromosomal instability.

Li, Jun; Hubisz, Melissa J; Earlie, Ethan M; Duran, Mercedes A; Hong, Christy; Varela, Austin A; Lettera, Emanuele; Deyell, Matthew; Tavora, Bernardo; Havel, Jonathan J; Phyu, Su M; Amin, Amit Dipak; Budre, Karolina; Kamiya, Erina; Cavallo, Julie-Ann; Garris, Christopher; Powell, Simon; Reis-Filho, Jorge S; Wen, Hannah; Bettigole, Sarah; Khan, Atif J; Izar, Benjamin; Parkes, Eileen E; Laughney, Ashley M; Bakhoum, Samuel F.

Nature ; 620(7976): 1080-1088, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37612508

2.

The evolution of the human DNA replication timing program.

Bracci, Alexa N; Dallmann, Anissa; Ding, Qiliang; Hubisz, Melissa J; Caballero, Madison; Koren, Amnon.

Proc Natl Acad Sci U S A ; 120(10): e2213896120, 2023 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-36848554

3.

Mapping gene flow between ancient hominins through demography-aware inference of the ancestral recombination graph.

Hubisz, Melissa J; Williams, Amy L; Siepel, Adam.

PLoS Genet ; 16(8): e1008895, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32760067

4.

Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps.

Hejase, Hussein A; Salman-Minkov, Ayelet; Campagna, Leonardo; Hubisz, Melissa J; Lovette, Irby J; Gronau, Ilan; Siepel, Adam.

Proc Natl Acad Sci U S A ; 117(48): 30554-30565, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33199636

5.

Ancient gene flow from early modern humans into Eastern Neanderthals.

Kuhlwilm, Martin; Gronau, Ilan; Hubisz, Melissa J; de Filippo, Cesare; Prado-Martinez, Javier; Kircher, Martin; Fu, Qiaomei; Burbano, Hernán A; Lalueza-Fox, Carles; de la Rasilla, Marco; Rosas, Antonio; Rudan, Pavao; Brajkovic, Dejana; Kucan, Zeljko; Gusic, Ivan; Marques-Bonet, Tomas; Andrés, Aida M; Viola, Bence; Pääbo, Svante; Meyer, Matthias; Siepel, Adam; Castellano, Sergi.

Nature ; 530(7591): 429-33, 2016 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-26886800

6.

Parallel evolution of ancient, pleiotropic enhancers underlies butterfly wing pattern mimicry.

Lewis, James J; Geltman, Rachel C; Pollak, Patrick C; Rondem, Kathleen E; Van Belleghem, Steven M; Hubisz, Melissa J; Munn, Paul R; Zhang, Linlin; Benson, Caleb; Mazo-Vargas, Anyi; Danko, Charles G; Counterman, Brian A; Papa, Riccardo; Reed, Robert D.

Proc Natl Acad Sci U S A ; 116(48): 24174-24183, 2019 11 26.

Artigo em Inglês | MEDLINE | ID: mdl-31712408

7.

SweepFinder2: increased sensitivity, robustness and flexibility.

DeGiorgio, Michael; Huber, Christian D; Hubisz, Melissa J; Hellmann, Ines; Nielsen, Rasmus.

Bioinformatics ; 32(12): 1895-7, 2016 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-27153702

8.

A high-resolution map of human evolutionary constraint using 29 mammals.

Lindblad-Toh, Kerstin; Garber, Manuel; Zuk, Or; Lin, Michael F; Parker, Brian J; Washietl, Stefan; Kheradpour, Pouya; Ernst, Jason; Jordan, Gregory; Mauceli, Evan; Ward, Lucas D; Lowe, Craig B; Holloway, Alisha K; Clamp, Michele; Gnerre, Sante; Alföldi, Jessica; Beal, Kathryn; Chang, Jean; Clawson, Hiram; Cuff, James; Di Palma, Federica; Fitzgerald, Stephen; Flicek, Paul; Guttman, Mitchell; Hubisz, Melissa J; Jaffe, David B; Jungreis, Irwin; Kent, W James; Kostka, Dennis; Lara, Marcia; Martins, Andre L; Massingham, Tim; Moltke, Ida; Raney, Brian J; Rasmussen, Matthew D; Robinson, Jim; Stark, Alexander; Vilella, Albert J; Wen, Jiayu; Xie, Xiaohui; Zody, Michael C; Baldwin, Jen; Bloom, Toby; Chin, Chee Whye; Heiman, Dave; Nicol, Robert; Nusbaum, Chad; Young, Sarah; Wilkinson, Jane; Worley, Kim C.

Nature ; 478(7370): 476-82, 2011 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-21993624

9.

Genome-wide inference of ancestral recombination graphs.

Rasmussen, Matthew D; Hubisz, Melissa J; Gronau, Ilan; Siepel, Adam.

PLoS Genet ; 10(5): e1004342, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24831947

10.

A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes.

Capra, John A; Hubisz, Melissa J; Kostka, Dennis; Pollard, Katherine S; Siepel, Adam.

PLoS Genet ; 9(8): e1003684, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23966869

11.

Proportionally more deleterious genetic variation in European than in African populations.

Lohmueller, Kirk E; Indap, Amit R; Schmidt, Steffen; Boyko, Adam R; Hernandez, Ryan D; Hubisz, Melissa J; Sninsky, John J; White, Thomas J; Sunyaev, Shamil R; Nielsen, Rasmus; Clark, Andrew G; Bustamante, Carlos D.

Nature ; 451(7181): 994-7, 2008 Feb 21.

Artigo em Inglês | MEDLINE | ID: mdl-18288194

12.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation.

Gardner, Eric E; Earlie, Ethan M; Li, Kate; Thomas, Jerin; Hubisz, Melissa J; Stein, Benjamin D; Zhang, Chen; Cantley, Lewis C; Laughney, Ashley M; Varmus, Harold.

Science ; 383(6683): eadj1415, 2024 Feb 09.

Artigo em Inglês | MEDLINE | ID: mdl-38330136

13.

The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome.

Kostka, Dennis; Hubisz, Melissa J; Siepel, Adam; Pollard, Katherine S.

Mol Biol Evol ; 29(3): 1047-57, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22075116

14.

Replacing and additive horizontal gene transfer in Streptococcus.

Choi, Sang Chul; Rasmussen, Matthew D; Hubisz, Melissa J; Gronau, Ilan; Stanhope, Michael J; Siepel, Adam.

Mol Biol Evol ; 29(11): 3309-20, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22617954

15.

Detection of nonneutral substitution rates on mammalian phylogenies.

Pollard, Katherine S; Hubisz, Melissa J; Rosenbloom, Kate R; Siepel, Adam.

Genome Res ; 20(1): 110-21, 2010 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19858363

16.

PHAST and RPHAST: phylogenetic analysis with space/time models.

Hubisz, Melissa J; Pollard, Katherine S; Siepel, Adam.

Brief Bioinform ; 12(1): 41-51, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21278375

17.

A simple genetic architecture underlies morphological variation in dogs.

Boyko, Adam R; Quignon, Pascale; Li, Lin; Schoenebeck, Jeffrey J; Degenhardt, Jeremiah D; Lohmueller, Kirk E; Zhao, Keyan; Brisbin, Abra; Parker, Heidi G; vonHoldt, Bridgett M; Cargill, Michele; Auton, Adam; Reynolds, Andy; Elkahloun, Abdel G; Castelhano, Marta; Mosher, Dana S; Sutter, Nathan B; Johnson, Gary S; Novembre, John; Hubisz, Melissa J; Siepel, Adam; Wayne, Robert K; Bustamante, Carlos D; Ostrander, Elaine A.

PLoS Biol ; 8(8): e1000451, 2010 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-20711490

18.

Evolutionary genomics: detecting selection needs comparative data.

Nielsen, Rasmus; Hubisz, Melissa J.

Nature ; 433(7023): E6; discussion E7-8, 2005 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-15662372

19.

Patterns of positive selection in six Mammalian genomes.

Kosiol, Carolin; Vinar, Tomás; da Fonseca, Rute R; Hubisz, Melissa J; Bustamante, Carlos D; Nielsen, Rasmus; Siepel, Adam.

PLoS Genet ; 4(8): e1000144, 2008 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-18670650

20.

Targets of balancing selection in the human genome.

Andrés, Aida M; Hubisz, Melissa J; Indap, Amit; Torgerson, Dara G; Degenhardt, Jeremiah D; Boyko, Adam R; Gutenkunst, Ryan N; White, Thomas J; Green, Eric D; Bustamante, Carlos D; Clark, Andrew G; Nielsen, Rasmus.

Mol Biol Evol ; 26(12): 2755-64, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19713326

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