Detalhe da pesquisa
1.
A Gut-Intrinsic Melanocortin Signaling Complex Augments L-Cell Secretion in Humans.
Gastroenterology
; 161(2): 536-547.e2, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33848536
2.
Augmented capacity for peripheral serotonin release in human obesity.
Int J Obes (Lond)
; 42(11): 1880-1889, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29568107
3.
Pharmacokinetics and pharmacodynamics of PF-05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects.
Br J Clin Pharmacol
; 83(2): 326-338, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621150
4.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
J Med Chem
; 65(12): 8208-8226, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647711
5.
Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.
Am J Physiol Endocrinol Metab
; 301(2): E380-90, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21586699
6.
Neuropeptide modulation of a lumbar spinal reflex: potential implications for female sexual function.
J Sex Med
; 6(4): 947-957, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19170864
7.
Sugar Responses of Human Enterochromaffin Cells Depend on Gut Region, Sex, and Body Mass.
Nutrients
; 11(2)2019 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678223
8.
Latest approaches for the treatment of obesity.
Expert Opin Drug Discov
; 10(8): 825-39, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25967138
9.
Bretylium or 6-OHDA-resistant, action potential-evoked Ca2+ transients in varicosities of the mouse vas deferens.
Br J Pharmacol
; 135(8): 1845-50, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11959786
10.
Regional variation in electrically-evoked contractions of rabbit isolated pulmonary artery.
Br J Pharmacol
; 137(4): 488-96, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12359630
11.
Investigational drugs in Phase II clinical trials for the treatment of obesity: implications for future development of novel therapies.
Expert Opin Investig Drugs
; 23(8): 1055-66, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25000213
12.
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate.
ACS Med Chem Lett
; 5(5): 474-9, 2014 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900864
13.
Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes.
Diabetes
; 62(9): 3005-13, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23970519
14.
Leptin potentiates the anti-obesity effects of rimonabant.
Eur J Pharmacol
; 658(2-3): 270-6, 2011 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21371466
15.
Correlation of non-uniform protein expression with variation in transmitter release probability.
Synapse
; 55(2): 110-21, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15543629
16.
Intermittent ATP release from nerve terminals elicits focal smooth muscle Ca2+ transients in mouse vas deferens.
J Physiol
; 541(Pt 3): 849-62, 2002 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12068045