Detalhe da pesquisa
1.
HIF-PHD inhibitor desidustat ameliorates iron deficiency anemia.
Toxicol Appl Pharmacol
; 483: 116832, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266872
2.
Unveiling stress markers: A systematic review investigating psychological stress biomarkers.
Dev Psychobiol
; 66(5): e22490, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38680082
3.
Safety Assessment of a Novel Intravenous Diclofenac Sodium Formulation Following 28-Day Repeated Administration in Wistar Rats.
Int J Toxicol
; : 10915818241261922, 2024 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38901831
4.
A Retrospective Comparison of Electrocardiographic Parameters in Ketamine and Tiletamine-Zolazepam Anesthetized Indian Rhesus Monkeys (Macaca mulatta).
Int J Toxicol
; 43(2): 184-195, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38108647
5.
Needle-free injection system delivery of ZyCoV-D DNA vaccine demonstrated improved immunogenicity and protective efficacy in rhesus macaques against SARS-CoV-2.
J Med Virol
; 95(2): e28484, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36625386
6.
High-field ex vivo and in vivo two-dimensional nuclear magnetic resonance spectroscopy in murine brain: Resolving and exploring the molecular environment.
NMR Biomed
; 36(2): e4833, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114827
7.
Saroglitazar suppresses the hepatocellular carcinoma induced by intraperitoneal injection of diethylnitrosamine in C57BL/6 mice fed on choline deficient, l-amino acid- defined, high-fat diet.
BMC Cancer
; 23(1): 59, 2023 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36650455
8.
Design, synthesis and biological evaluation of novel pyrazolo-pyrimidin-amines as potent and selective BTK inhibitors.
Bioorg Chem
; 130: 106238, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36403335
9.
Comparison of different QT correction methods for nonclinical safety assessment in ketamine-anesthetized Indian rhesus monkeys (Macaca mulatta).
Toxicol Mech Methods
; 33(6): 490-501, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36879461
10.
Microsomal triglyceride transfer protein inhibitor lomitapide-induced liver toxicity is ameliorated by Triiodothyronine treatment following improved bile homeostasis and ß-oxidation.
Toxicol Appl Pharmacol
; 434: 115825, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34902352
11.
Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor.
Bioorg Med Chem Lett
; 66: 128728, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35413417
12.
Discovery of novel, potent and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19).
Bioorg Med Chem Lett
; 53: 128421, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34718128
13.
Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes.
Bioorg Med Chem
; 35: 116071, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33611013
14.
Simultaneous determination of sacubitrilat and fimasartan in rat plasma by a triple quad liquid chromatography-tandem mass spectrometry method utilizing electrospray ionization in positive mode.
Biomed Chromatogr
; 35(2): e4981, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32895916
15.
Role of mineralocorticoid receptor antagonists in kidney diseases.
Drug Dev Res
; 82(3): 341-363, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33179798
16.
Prolyl hydroxylase inhibitor desidustat protects against acute and chronic kidney injury by reducing inflammatory cytokines and oxidative stress.
Drug Dev Res
; 82(6): 852-860, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33480036
17.
Leprosy drug clofazimine activates peroxisome proliferator-activated receptor-γ and synergizes with imatinib to inhibit chronic myeloid leukemia cells.
Haematologica
; 105(4): 971-986, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371410
18.
Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor.
Bioorg Med Chem Lett
; 30(21): 127571, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980515
19.
Relevance of preclinical rodent pharmacokinetics in the selection of a companion antibiotic for combining with beta-lactamase inhibitor.
Xenobiotica
; 50(7): 815-821, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31755347
20.
Deletion of Htt cause alterations in cAMP signaling and spatial patterning in Dictyostelium discoideum.
J Cell Physiol
; 234(10): 18858-18871, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30916411