Detalhe da pesquisa
1.
Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.
Immunity
; 52(2): 357-373.e9, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32049051
2.
Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window.
J Med Chem
; 59(11): 5520-41, 2016 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27167326
3.
Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.
ACS Med Chem Lett
; 6(12): 1241-6, 2015 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26713112
4.
P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma.
J Natl Cancer Inst
; 105(9): 606-7, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23535073
5.
Combination drug scheduling defines a "window of opportunity" for chemopotentiation of gemcitabine by an orally bioavailable, selective ChK1 inhibitor, GNE-900.
Mol Cancer Ther
; 12(10): 1968-80, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873850