Detalhe da pesquisa
1.
Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer.
PLoS Genet
; 12(4): e1005895, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27093186
2.
A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients.
Ann Rheum Dis
; 73(1): 256-62, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23434567
3.
Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus.
Arthritis Rheum
; 64(11): 3715-25, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22736314
4.
A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.
Br J Haematol
; 155(4): 426-37, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21902688
5.
Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study.
Ann Rheum Dis
; 70(11): 1905-13, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21798883
6.
Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway.
Ann Rheum Dis
; 70(11): 2029-36, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21803750
7.
Interferon-stimulated gene 15 (ISG15) conjugates proteins in dermatomyositis muscle with perifascicular atrophy.
Ann Neurol
; 67(1): 53-63, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20186858
8.
Human plasmacytoid dendritic cell accumulation amplifies their type 1 interferon production.
Clin Immunol
; 136(1): 130-8, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346735
9.
B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.
J Pharmacol Exp Ther
; 335(1): 213-22, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20605905
10.
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells.
Blood
; 112(3): 711-20, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18497318
11.
Permissive environment for B-cell maturation in myositis muscle in the absence of B-cell follicles.
Muscle Nerve
; 42(4): 576-83, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20740627
12.
The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion.
Mol Cell Biol
; 23(6): 2068-82, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12612079
13.
CHIR-258 is efficacious in a newly developed fibroblast growth factor receptor 3-expressing orthotopic multiple myeloma model in mice.
Clin Cancer Res
; 12(16): 4908-15, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16914579
14.
The Ste20 kinase MST4 plays a role in prostate cancer progression.
Cancer Res
; 63(12): 3356-63, 2003 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12810671
15.
A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.
Mol Cancer Ther
; 15(4): 689-701, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880266
16.
In Vivo Therapeutic Success of MicroRNA-155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage.
Arthritis Rheumatol
; 68(4): 953-64, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26556607
17.
Identification of Cyclin-Dependent Kinase 1 as a Novel Regulator of Type I Interferon Signaling in Systemic Lupus Erythematosus.
Arthritis Rheumatol
; 68(5): 1222-32, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663909
18.
The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn).
Oncogene
; 21(46): 7067-76, 2002 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370829
19.
The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation.
Exp Hematol
; 30(3): 237-44, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11882361
20.
Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus.
Arthritis Rheumatol
; 67(12): 3209-18, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26315540