Detalhe da pesquisa
1.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Proc Natl Acad Sci U S A
; 119(49): e2123487119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454749
2.
Tau and neurofilament light-chain as fluid biomarkers in spinocerebellar ataxia type 3.
Eur J Neurol
; 29(8): 2439-2452, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35478426
3.
TRIO gene segregation in a family with cerebellar ataxia.
Neurol Neurochir Pol
; 52(6): 743-749, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279051
4.
Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.
Mov Disord
; 37(5): 1120-1121, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35587620
5.
Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.
Hum Mol Genet
; 23(6): 1467-78, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24163244
6.
Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
Proc Natl Acad Sci U S A
; 109(52): 21510-5, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23236149
7.
Erratum: Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19.
iScience
; 27(4): 109501, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38523775
8.
Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models.
Biomedicines
; 11(10)2023 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37893236
9.
Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19.
iScience
; 25(11): 105272, 2022 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36213006
10.
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19.
Sci Transl Med
; 13(602)2021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34131052
11.
Urine levels of the polyglutamine ataxin-3 protein are elevated in patients with spinocerebellar ataxia type 3.
Parkinsonism Relat Disord
; 89: 151-154, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303201
12.
Astrocyte-derived clusterin suppresses amyloid formation in vivo.
Mol Neurodegener
; 15(1): 71, 2020 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33246484
13.
Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.
Alzheimers Res Ther
; 12(1): 132, 2020 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069251
14.
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
Mol Neurodegener
; 15(1): 21, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32178712
15.
Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation.
Acta Neuropathol Commun
; 8(1): 210, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33261653
16.
Plasma neurofilament light predicts mortality in patients with stroke.
Sci Transl Med
; 12(569)2020 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33177179
17.
Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3.
Sci Transl Med
; 12(566)2020 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33087504
18.
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
Acta Neuropathol Commun
; 6(1): 42, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29855382
19.
Abnormal expression of homeobox genes and transthyretin in C9ORF72 expansion carriers.
Neurol Genet
; 3(4): e161, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28660252